| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.com |
| Products Intro: |
Product Name:Piriprost
CAS:79672-88-1
Purity:详情请点击官网 Package:1 mg
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| | Piriprost Basic information |
| Product Name: | Piriprost | | Synonyms: | (4R)-1,4,5,6-Tetrahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-1-octenyl]-1-phenylcyclopenta[b]pyrrole-2-pentanoic acid;(4R)-1,4,5,6-Tetrahydro-5α-hydroxy-4β-[(E,S)-3-hydroxy-1-octenyl]-1-phenylcyclopenta[b]pyrrole-2-pentanoic acid;U-60257;Cyclopenta(B)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-((1E,3S)-3-hydroxy-1-octenyl)-1-phenyl-, (4R,5R)-;Cyclopenta(B)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-1-phenyl-, (4R-(4alpha(1E,3S*),5beta))-;Piriprostium;Piriprostium [latin];Unii-R802o5nilk | | CAS: | 79672-88-1 | | MF: | C26H35NO4 | | MW: | 425.565 | | EINECS: | | | Product Categories: | | | Mol File: | 79672-88-1.mol |  |
| | Piriprost Chemical Properties |
| | Piriprost Usage And Synthesis |
| Uses | Anti-asthmatic. | | Enzyme inhibitor | This lipoxygenase-inhibiting pyrrole analogue of prostacyclin (FWpotassium salt = 463.66 g/mol; CAS 79672-88-1), also known as U60257B and 6,9- deepoxy-6,9-(phenylimino)-D6,8-prostaglandin I1, [4R-[4a(1E,3S*),5b]]- 1,4,5,6-tetrahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-1-phenylcyclopenta[ b]pyrrole-2-pentanoate, inhibits leukotriene C and D formation.1-5 Piriprost also inhibits the release of histamine and leukotrienes from isolated porcine lung cells.6 Note that both priprost and its methyl ester (U-56467) inhibit leukotriene biosynthesis: ID50 = 4.6 and 0.31 μM, respectively. Target(s): glutathione S-transferase; and 5- lipoxygenase, or arachidonate 5-lipoxygenase. |
| | Piriprost Preparation Products And Raw materials |
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