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| CAPTOPRIL DISULFIDE Basic information |
| CAPTOPRIL DISULFIDE Chemical Properties |
Melting point | 224-226°C | Boiling point | 714.8±60.0 °C(Predicted) | density | 1.383±0.06 g/cm3(Predicted) | storage temp. | -20°C Freezer | solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated) | pka | 3.29±0.20(Predicted) | color | White to Off-White |
WGK Germany | 3 | HS Code | 2933999552 |
| CAPTOPRIL DISULFIDE Usage And Synthesis |
Description | Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril . Captopril disulfide is the main degradation product of captopril and is formed by oxidation. It is a potential impurity in commercial preparations of captopril. Captopril disulfide inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg, i.v.). | Chemical Properties | White Solid | Uses | Captopril Disulfide (Captopril EP Impurity A) is a metabolite of Captopril. A new antihypertensive agent. | Definition | ChEBI: An organic disulfide in which the disulfide bond links two units of captopril. It is a secondary metabolite of captopril. |
| CAPTOPRIL DISULFIDE Preparation Products And Raw materials |
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