bis(N-benzyloxycarbonyltetraalanyl)rhodamine

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Products Intro: Product Name:(Z-Ala-Ala-Ala-Ala)2Rh110
CAS:149695-85-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Products Intro: Product Name:bis(N-benzyloxycarbonyltetraalanyl)rhodamine
CAS:149695-85-2
Purity:98% Package:5mg; 10mg Remarks:Medbio
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Products Intro: Product Name:(Z-Ala-Ala-Ala-Ala)2Rhodamine110
CAS:149695-85-2
Purity:98% Package:1KG;100g;1g,100mg
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Products Intro: Product Name:bis(N-benzyloxycarbonyltetraalanyl)rhodamine
CAS:149695-85-2
Purity:95+% Package:1g;5g
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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Products Intro: Product Name:(Z-Ala-Ala-Ala-Ala)2Rh110
CAS:149695-85-2
Purity:95% Package:1mg;5mg;10mg
bis(N-benzyloxycarbonyltetraalanyl)rhodamine Basic information
Product Name:bis(N-benzyloxycarbonyltetraalanyl)rhodamine
Synonyms:bis(N-benzyloxycarbonyltetraalanyl)rhodamine;JGBISHWUFSPAPR-UHFFFAOYSA-N;L-Alaninamide, 4,4'-(3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl)bis[N-[(phenylmethoxy)carbonyl]-L-alanyl-L-alanyl-L-alanyl-;(Z-Ala-Ala-Ala-Ala)2Rhodamine110
CAS:149695-85-2
MF:C60H66N10O15
MW:1167.22
EINECS:
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Mol File:149695-85-2.mol
bis(N-benzyloxycarbonyltetraalanyl)rhodamine Structure
bis(N-benzyloxycarbonyltetraalanyl)rhodamine Chemical Properties
storage temp. Store at -20°C,protect from light
solubility ≤2mg/ml in DMSO;2mg/ml in dimethyl formamide
form crystalline solid
Safety Information
MSDS Information
bis(N-benzyloxycarbonyltetraalanyl)rhodamine Usage And Synthesis
Description(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.
in vitro(z-ala-ala-ala-ala)2rh110 has been identified as a very sensitive fluorogenic elastase substrate. the colorless and nonfluorescent z-ala-ala-ala-ala)2rh110 was found to be selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which exhibited excellent spectral properties matching the optimal detection window of most fluorescence instruments. after cleavage, abs(max) is at 497 nm and em(max) is at 520 nm for rhodamine 110 [1].
references[1] a. f. johnson, m. d. struthers, k. b. pierson, et al. nonisotopic dna detection system employing elastase and a fluorogenic rhodamine substrate. analytical chemistry 65, 2352-2359 (1993).
bis(N-benzyloxycarbonyltetraalanyl)rhodamine Preparation Products And Raw materials
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