| Product Name: | HU-210 | | Synonyms: | (-)-11-OH-Δ8-THC-1,1-dimethylheptyl;(6aR)-6aβ,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol;(6aR)-6aβ,7,10,10aα-Tetrahydro-6,6-dimethyl-1-hydroxy-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol;[6aR,(-)]-6a,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol;11-OH-Δ8-THC-1,1-dimethylheptyl;(6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol;HU-210 DEA Schedule I;(6aR)-trans-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-(6H)-dibenzo[b.d]pyran-9-methanol | | CAS: | 112830-95-2 | | MF: | C25H38O3 | | MW: | 386.57 | | EINECS: | 200-659-6 | | Product Categories: | Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Cannabinoid receptor | | Mol File: | 112830-95-2.mol |  |
| | HU-210 Chemical Properties |
| Boiling point | 470.1±45.0 °C(Predicted) | | density | 1.030±0.06 g/cm3(Predicted) | | Fp | 9℃ | | storage temp. | −20°C | | solubility | DMSO: soluble | | pka | 9.72±0.60(Predicted) | | form | solid | | BRN | 4298162 | | Stability: | Hygroscopic |
| | HU-210 Usage And Synthesis |
| Description | HU-210 (exempt preparation) (Item No. 90083) is an analytical reference standard categorized as a synthetic cannabinoid. HU-210 is regulated as a Schedule I compound in the United States. HU-210 (exempt preparation) (Item No. 90083) is provided as a DEA exempt preparation. This product is intended for research and forensic applications. | | Chemical Properties | liquid | | Uses | A synthetic agonist analog of ?9-Tetrahydro Cannabinol (T293200), which is the primary psychoactive component of marijuana. HU-210 is a potent central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist. It binds to neuroblastoma cell membrane CB1 receptors with about the same affinity as CP-55940.
Controlled Substance. | | Definition | ChEBI: HU-210 is a 1-benzopyran. | | Biological Activity | A highly potent cannabinoid receptor agonist (K i values are 0.061 and 0.52 nM at cloned human CB 1 and CB 2 receptors respectively). Induces spatial memory deficits and suppresses hippocampal firing rates in rats. Also displays agonist activity at GPR55 (EC 50 = 26 nM). Also available as part of the Cannabinoid Receptor Agonist Tocriset™ . | | References | [1] D M SLIPETZ. Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase.[J]. Molecular Pharmacology, 1995, 48 2: 352-361.
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| | HU-210 Preparation Products And Raw materials |
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