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(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate

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(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Suppliers list
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Zaurategrast ethyl ester；UCB1184197;CDP323
CAS:455264-30-9
Package:10 mg；100 mg；25 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Chembest Research Laboratories Limited  
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Products Intro: Product Name:Zaurategrast Ethyl Ester (CDP323
CAS:455264-30-9
Purity:98%+ Package:50mg;100mg;500mg;1g;5g;10g
Company Name: Haoyuan Chemexpress Co., Ltd.  
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Products Intro: Product Name:(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylamino)phenyl)-2-(2-bromo-3-oxospiro[3.5]non-1-en-1-ylamino)propanoate
CAS:455264-30-9
Purity:>98% Package:2967RMB/25mg
Company Name: Cool Pharm, Ltd  
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Products Intro: Product Name:(S)-ethyl3-(4-((2,7-naphthyridin-1-yl)amino)phenyl)-2-((2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino)propanoate
CAS:455264-30-9
Purity:97.0% Package:10g;25g;100g;500g;1kg;5kg;10kg
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
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Products Intro: Product Name:(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
CAS:455264-30-9
Purity:97.0% Package:5mg
(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Basic information
Product Name:(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
Synonyms:(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate;UCB1184197);Zaurategrast ethyl ester (Synonyms: CDP323;Zaurategrast Ethyl Ester (CDP323;Zaurategrast ethyl ester;L-Phenylalanine, N-(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylamino)-, ethyl ester
CAS:455264-30-9
MF:C28H29BrN4O3
MW:549.46
EINECS:
Product Categories:
Mol File:455264-30-9.mol
(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Structure
(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Chemical Properties
Melting point 192.5-195 °C
Boiling point 698.2±55.0 °C(Predicted)
density 1.44±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 150 mg/mL (273.00 mM); Water: < 0.1 mg/mL (insoluble)
pka4.84±0.30(Predicted)
Safety Information
MSDS Information
(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Usage And Synthesis
Biological ActivityZaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, is an α4β1/α4β7 integrin antagonist for the study of inflammatory and autoimmune diseases.
in vitro

Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer.

target

α4β1/α4β7 integrin

(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Preparation Products And Raw materials
Tag:(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate(455264-30-9) Related Product Information
L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1 DEMETON S