|
ChemicalBook Optimization Suppliers |
|
| 化学名: | セフォジジムナトリウム | | 英語化学名: | Cefodizime sodium | | 别名: | )(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio;7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)th5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicaci;7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid;disodiumsalt,(6r-(6-alpha,7-beta(z)))-)methyl)-8-oxo;thr-221;7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid disodium salt;Cefodizimedisodiumsalt;kenicef | | CAS番号: | 86329-79-5 | | 分子式: | C20H21N6NaO7S4 | | 分子量: | 608.65 | | EINECS: | | | カテゴリ情報: | | | Mol File: | 86329-79-5.mol |  |
| 毒性 | LD50 in mice, rabbits (mg/kg): 4000-8000 i.v. both species; in rats (mg/kg): 4000-8000 i.v., 15000-17500 s.c., 8000-11000 i.p. (Bryskier) |
| | セフォジジムナトリウム Usage And Synthesis |
| 効能 | 抗生物質, 細胞壁合成阻害薬 | | 説明 | Cefodizirne sodium is a parenteral, long-acting, broad-spectrum cephalosporin useful in the treatment of bacterial infections. It is efficacious against pathogens resistant to
penicillins and older cephalosporins. An indication under study is its reported
immunostimulatory activity. | | Originator | Hoechst AG (Germany) | | 使用 | Cefodizime Sodium (cas# 86329-79-5) is a compound useful in organic synthesis. | | 定義 | ChEBI: Cefodizime sodium is a cephalosporin. | | brand name | Neucef; Kenicef | | 危険性 | Low toxicity by ingestion. | | Biochem/physiol Actions | Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime was demonstrated to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea. Cefodizime regulates the cytokines expression of neutrophils through toll-like receptor 4 (TLR-4) stimulated by Klebsiella pneumonie. |
|