| Company Name: |
Bide Pharmatech Ltd.
|
| Tel: |
400-164-7117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS:2136270-20-5
Purity:99% Package:5mg;10mg;25mg;50mg;100mg Remarks:BD01281841
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:SPOP-IN-6b
CAS:2136270-20-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
SPOP-IN-6b manufacturers
- SPOP-IN-6b
-
- $94.00 / 1mg
-
2025-11-10
- CAS:2136270-20-5
- Min. Order:
- Purity: 99.93%
- Supply Ability: 10g
|
| | SPOP-IN-6b Basic information |
| Product Name: | SPOP-IN-6b | | Synonyms: | SPOP-IN-6b;2H-Dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide, 1,5-dihydro-2-imino-10-methyl-N-[3-(4-morpholinyl)propyl]-5-oxo-1-(2-phenylethyl)-;2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide;SPOP-IN-6b, 10 mM in DMSO;6-imino-11-methyl-N-[3-(morpholin-4-yl)propyl]-2-oxo-7-(2-phenylethyl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide - [AC78124] | | CAS: | 2136270-20-5 | | MF: | C28H32N6O3 | | MW: | 500.59 | | EINECS: | | | Product Categories: | | | Mol File: | 2136270-20-5.mol |  |
| | SPOP-IN-6b Chemical Properties |
| density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 10 mg/mL (19.98 mM) | | pka | 11.90±0.20(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | SPOP-IN-6b Usage And Synthesis |
| Uses | SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM (patent CN 107141287, SPOP-B-88)[1]. | | in vivo | SPOP-IN-6b (40-80 mg/kg; i.p.; daily; for 25 days) can slow down the growth of tumour by suppressing SPOP[1].
| Animal Model: | Nude mice[1] | | Dosage: | 40 mg/kg, 60 mg/kg, 80 mg/kg | | Administration: | Intraperitoneal injection; daily; for 25 days | | Result: | Slowed down the growth of tumour by suppressing SPOP. |
| | References | [1] Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A. |
| | SPOP-IN-6b Preparation Products And Raw materials |
|