β淀粉样蛋白 (1-15)
| 中文名称 | β淀粉样蛋白 (1-15) |
|---|---|
| 中文同义词 | Β淀粉样蛋白(1-15);Β淀粉样肽(1-15) |
| 英文名称 | AMYLOID BETA-PROTEIN (1-15) |
| 英文同义词 | AMYLOID BETA-PROTEIN (1-15);H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-OH;AMyloid b-Protein (1-15);Amyloid beta-Protein (1-15) trifluoroacetate salt;L-Glutamine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-;β-Amyloid 1-15;Amyloid β-Protein (1-15);Aβ1-15 |
| CAS号 | 183745-81-5 |
| 分子式 | C78H107N25O27 |
| 分子量 | 1826.86 |
| EINECS号 | |
| 相关类别 | Neuroscience |
| Mol文件 | 183745-81-5.mol |
| 结构式 |  |
β淀粉样蛋白 (1-15) 性质
| 密度 | 1.59±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | Store at -20°C |
| 溶解度 | 不溶于乙醇； DMSO 中≥182.6 mg/mL；水中≥50.7 mg/mL |
| 形态 | 固体 |
β-Amyloid (1-15) 是β-淀粉样蛋白片段。 β-淀粉样蛋白是在阿尔茨海默病患者的脑中形成淀粉样斑块的肽。
Amyloid-β
β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. .