NAFAMOSTAT MESYLATE | China | Manufacturer | Henan Fengda Chemical Co., Ltd

Price	$8	$5	$1
Package	1kg	25kg	100kg

Product Details

Product Name: NAFAMOSTAT MESYLATE	CAS No.: 81525-10-2
Min. Order: 1kg	Purity: 99%
Supply Ability: g-kg-tons, free sample is available	Release date: 2024/04/05
Lead time: In stock	Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express	Origin: Manufacturer
NAME: Sun

1. Product information

Name	nafamostat mesylate
Synonym	More Synonyms

Description	Nafamostat is a broad spectrum serine protease inhibitor, kallikrein inhibitor, and inhibits blood coagulation; is also a possible complement inhibitor.Target: Serine ProteaseTranilast (FUT-175) is an antiallergic drug for bronchial asthma. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. It has also been investigated for use as an antiproliferative drug on drug-eluting stents.A 20-40 mg/h dose of FUT-175 prolonged coagulation time sufficiently in the instrumental blood of the extracorporeal circuit but not in the systemic blood. Its anticoagulant activity decreased immediately after hemodialysis. Therefore, we could manage all patients without any bleeding trouble during hemodialysis with FUT-175 as an anticoagulant. Although there were side effects of FUT-175, such as nausea, vomiting, itching and eruption, they were not serious, and FUT-175 could be administered without interruption. FUT-175 seems to be useful as an anticoagulant during hemodialysis for patients susceptible to bleeding.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cardiovascular Disease
References	[1]. Ikehara S, et al. Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology. 1985 Aug;55(4):595-600. [2]. Pak K, et al. Effectiveness of FUT-175, protease inhibitor, as an anticoagulant to hemodialysis. Hinyokika Kiyo. 1988 Jun;34(6):1077-81.

Description

Nafamostat is a broad spectrum serine protease inhibitor, kallikrein inhibitor, and inhibits blood coagulation; is also a possible complement inhibitor.Target: Serine ProteaseTranilast (FUT-175) is an antiallergic drug for bronchial asthma. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. It has also been investigated for use as an antiproliferative drug on drug-eluting stents.A 20-40 mg/h dose of FUT-175 prolonged coagulation time sufficiently in the instrumental blood of the extracorporeal circuit but not in the systemic blood. Its anticoagulant activity decreased immediately after hemodialysis. Therefore, we could manage all patients without any bleeding trouble during hemodialysis with FUT-175 as an anticoagulant. Although there were side effects of FUT-175, such as nausea, vomiting, itching and eruption, they were not serious, and FUT-175 could be administered without interruption. FUT-175 seems to be useful as an anticoagulant during hemodialysis for patients susceptible to bleeding.

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease

Research Areas >> Cardiovascular Disease

References

[1]. Ikehara S, et al. Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology. 1985 Aug;55(4):595-600.

[2]. Pak K, et al. Effectiveness of FUT-175, protease inhibitor, as an anticoagulant to hemodialysis. Hinyokika Kiyo. 1988 Jun;34(6):1077-81.

Density	1.4±0.1 g/cm3
Boiling Point	637.2±65.0 °C at 760 mmHg
Molecular Formula	C19H17N5O2
Molecular Weight	347.371
Flash Point	339.1±34.3 °C
Exact Mass	347.138214
PSA	138.07000
LogP	1.93
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.694
Storage condition	2-8℃

6-Carbamimidoyl-2-naphthyl 4-carbamimidamidobenzoate

6-carbamimidoylnaphthalen-2-yl 4-carbamimidamidobenzoate

Nafamostat Dimethanesulfonate

NAFAMOSTAT MESILATE

Benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester

6-Amidino-2-naphthyl-4-guanidinobenzoate

Futhan

6-AMIDINO-2-NAPHTHYL-4-GUANIDINOENZOATE,MESYLATE

Nafamstat

Nafamostat

6-carbamimidoylnaphthalen2-yl 4-(diaminomethyleneamino) benzoate

FUT-175

6-Amidino-2-naphthyl 4-guanidinobenzoate

NafamostatMesilateBase

4-[(Aminoiminomethyl)amino]benzoic Acid 6-(Aminoiminomethyl)-2-naphthalenyl Ester

4-Guanidinobenzoic acid 6-amidino-2-naphtyl ester

2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

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3. Shipping

Article illustration

4. Contact information

For more details, pls contact us freely.

Email address : sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137

Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

Recommended supplier

Product name	Price		Suppliers	Update time
Nafamostat	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-07-10
NAFAMOSTAT MESYLATE	$1.00/1g	VIP5Y	Career Henan Chemical Co	2019-12-25
Nafamostat	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-07-09

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Henan Fengda Chemical Co., Ltd

Min. Order:	1kg
Supply Ability:	g-kg-tons, free sample is available
Update Time:	2024-04-05