Tetracine Hydrochloride

99% Tetracaine Hydrochloride, Tetracaine HCl, CAS 136-47-0

Product Description
Tetracaine HCl
Alias: Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride;
4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride
CAS NO.: 136-47-0
EINECS: 205-248-5
MF: C15H25ClN2O2
MW: 300.82
MS:
 
Melting point: 149°C
Assay: 99%
Grade: Pharmaceutical Grade
Storage: Closed, confined and shading preservation
Manufacturer: Quanao
Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.
 
 
Description

Tetracaine hydrochloride (TCH) is one of the potent local anaesthetics. A kinetic study of oxidation of tetracaine hydrochloride by sodium N-chlorobenzenesulfonamide (chloramine-B or CAB) has been carried in HClO4 medium at 303 K. The rate shows first-order dependence on , shows fractional-order dependence on , and is self-governing on acid concentration. Decrease of dielectric constant of the medium, by adding methanol, increased the rate. Variation of ionic strength and addition of benzenesulfonamide or NaCl have no significant effect on the rate. The reaction was studied at different temperatures and the activation parameters have been evaluated. The stoichiometry of the reaction was found to be 1 : 5 and the oxidation products were identified by spectral analysis. The conjugate free acid C6H5SO2NHCl of CAB is postulated as the reactive oxidizing species. The observed results have been explained by plausible mechanism and the related rate law has been deduced.