Active Pharmaceutical Ingredients (API), popularly  speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat  are  the finished drugs  through processing.

Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including  chemical synthetic drugs and natural chemical drugs.

Chemical  synthetic drugs can be divided into organic synthetic drugs and inorganic  synthetic drugs. Inorganic synthetic drugs are inorganic compounds (  very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of  drugs made by  basic organic chemical raw materials, through a series of organic chemical reactions  (such as aspirin, chloramphenicol, caffeine, etc.).

Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation,  which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have  the largest proportion,which are  the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients  decides whether the formulation is good or bad , so its quality standards are very strict  ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.

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Structure Chemical Name CAS MF
Luliconazole Luliconazole 187164-19-8 C14H9Cl2N3S2
Alibendol Alibendol 26750-81-2 C13H17NO4
Clevidipine butyrate Clevidipine butyrate 167221-71-8 C21H23Cl2NO6
Sofalcone Sofalcone 64506-49-6 C27H30O6
Sitagliptin Sitagliptin 486460-32-6 C16H15F6N5O
Ziprasidone hydrochloride monohydrate Ziprasidone hydrochloride monohydrate 138982-67-9 C21H24Cl2N4O2S
Etoricoxib Etoricoxib 202409-33-4 C18H15ClN2O2S
Canagliflozin Canagliflozin 842133-18-0 C24H25FO5S
PLX4032 PLX4032 918504-65-1 C23H18ClF2N3O3S
Olopatadine Olopatadine 113806-05-6 C21H23NO3
Nequinate Nequinate 13997-19-8 C22H23NO4
Sitagliptin phosphate monohydrate Sitagliptin phosphate monohydrate 654671-77-9 C16H18F6N5O5P
Dronedarone Dronedarone 141626-36-0 C31H44N2O5S
10-Hydroxycamptothecin 10-Hydroxycamptothecin 64439-81-2 C20H16N2O5
Afatinib (BIBW 2992) Afatinib (BIBW 2992) 439081-18-2 C24H25ClFN5O3
Crizotinib Crizotinib 877399-52-5 C21H22Cl2FN5O
Raloxifene Raloxifene 84449-90-1 C28H27NO4S
Zileuton Zileuton 111406-87-2 C11H12N2O2S
6-Aminopenicillanic acid 6-Aminopenicillanic acid 551-16-6 C8H12N2O3S
Eszopiclone Eszopiclone 138729-47-2 C17H17ClN6O3
Darifenacin Darifenacin 133099-04-4 C28H30N2O2
Oseltamivir phosphate Oseltamivir phosphate 204255-11-8 C16H31N2O8P
Alvimopan Alvimopan 156053-89-3 C25H32N2O4
Mitiglinide calcium dihydrate Mitiglinide calcium dihydrate 207844-01-7 C38H52CaN2O8
Isoprinosine Isoprinosine 36703-88-5 C24H34N6O9
Olaquindox Olaquindox 23696-28-8 C12H13N3O4
Citalopram hydrobromide Citalopram hydrobromide 59729-32-7 C20H22BrFN2O
Miglitol Miglitol 72432-03-2 C8H17NO5
FASUDIL FASUDIL 103745-39-7 C14H17N3O2S
Ulipristal Acetate Ulipristal Acetate 126784-99-4 C30H37NO4
GW-501516 GW-501516 317318-70-0 C21H18F3NO3S2
Pranlukast Pranlukast 103177-37-3 C27H23N5O4
Clopidogrel Clopidogrel 113665-84-2 C16H16ClNO2S
Topotecan hydrochloride Topotecan hydrochloride 119413-54-6 C23H24ClN3O5
Tafluprost Tafluprost 209860-87-7 C25H34F2O5
Lopinavir Lopinavir 192725-17-0 C37H48N4O5
Propiverine hydrochloride Propiverine hydrochloride 54556-98-8 C23H30ClNO3
Carbazochrome sodium sulfonate Carbazochrome sodium sulfonate 51460-26-5 C10H17N4NaO8S
Fingolimod hydrochloride Fingolimod hydrochloride 162359-56-0 C19H34ClNO2
Tiotropium bromide Tiotropium bromide 136310-93-5 C19H22BrNO4S2
Cabazitaxel Cabazitaxel 183133-96-2 C45H57NO14
Dapoxetine Dapoxetine 119356-77-3 C21H23NO
Pemetrexed Disodium Pemetrexed Disodium 150399-23-8 C20H22N5NaO6
10-Hydroxycamptothecin 10-Hydroxycamptothecin 19685-09-7 C20H16N2O5
6-Chloronicotinic acid 6-Chloronicotinic acid 5326-23-8 C6H4ClNO2
4-Aminophenylarsonic acid 4-Aminophenylarsonic acid 98-50-0 C6H8AsNO3
Modafinil Modafinil 68693-11-8 C15H15NO2S
Empagliflozin Empagliflozin 864070-44-0 C23H27ClO7
Promestriene Promestriene 39219-28-8 C22H32O2
Pirfenidone Pirfenidone 53179-13-8 C12H11NO
7-Ethyl-10-hydroxycamptothecin 7-Ethyl-10-hydroxycamptothecin 86639-52-3 C22H20N2O5
Exemestane Exemestane 107868-30-4 C20H24O2
2-Methylimidazole 2-Methylimidazole 693-98-1 C4H6N2
Saxagliptin Saxagliptin 361442-04-8 C18H25N3O2
Esomeprazole Esomeprazole 119141-88-7 C17H19N3O3S
Decoquinate Decoquinate 18507-89-6 C24H35NO5
Maraviroc Maraviroc 376348-65-1 C29H41F2N5O
Vildagliptin Vildagliptin 274901-16-5 C17H25N3O2
Imatinib mesylate Imatinib mesylate 220127-57-1 C30H35N7O4S
Vitamin B6 Vitamin B6 8059-24-3 C10H16N2O3S
Lornoxicam Lornoxicam 70374-39-9 C13H10ClN3O4S2
Bismuththiol Bismuththiol 1072-71-5 C2H2N2S3
2-[(Acetyloxy)methoxy]ethyl acetate 2-[(Acetyloxy)methoxy]ethyl acetate 59278-00-1 C7H12O5
Tirofiban hydrochloride monohydrate Tirofiban hydrochloride monohydrate 150915-40-5 C22H39ClN2O6S
Argatroban Argatroban 74863-84-6 C23H36N6O5S
Deferasirox Deferasirox 201530-41-8 C21H15N3O4
Gefitinib Gefitinib 184475-35-2 C22H24ClFN4O3
Montelukast sodium Montelukast sodium 151767-02-1 C35H37ClNNaO3S
Selumetinib Selumetinib 606143-52-6 C17H15BrClFN4O3
Lorcaserin hydrochloride Lorcaserin hydrochloride 846589-98-8 C11H15Cl2N
Seratrodast Seratrodast 112665-43-7 C22H26O4
Dolasetron mesylate Dolasetron mesylate 115956-13-3 C20H26N2O7S
2-Aminothiazole-4-acetic acid 2-Aminothiazole-4-acetic acid 29676-71-9 C5H6N2O2S
Geldanamycin Geldanamycin 30562-34-6 C29H40N2O9
Duloxetine Duloxetine 116539-59-4 C18H19NOS
Bortezomib Bortezomib 179324-69-7 C19H25BN4O4
1,3-Dibromo-5,5-dimethylhydantoin 1,3-Dibromo-5,5-dimethylhydantoin 77-48-5 C5H6Br2N2O2
1,3-Diacetoxy-2-(acetoxymethoxy)propane 1,3-Diacetoxy-2-(acetoxymethoxy)propane 86357-13-3 C10H16O7
Suplatast tosilate Suplatast tosilate 94055-76-2 C23H33NO7S2
Iguratimod Iguratimod 123663-49-0 C17H14N2O6S
Flibanserin Flibanserin 167933-07-5 C20H21F3N4O
Pranoprofen Pranoprofen 52549-17-4 C15H13NO3
Dabigatran Etexilate Mesylate Dabigatran Etexilate Mesylate 872728-81-9 C35H45N7O8S
Rubitecan Rubitecan 91421-42-0 C20H15N3O6
Simvastatin Simvastatin 79902-63-9 C25H38O5
Quinine Quinine 130-95-0 C20H24N2O2
Hydrocortisone Hydrocortisone 50-23-7 C21H30O5
Terbinafine Hydrochloride Terbinafine Hydrochloride 78628-80-5 C21H26ClN
3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one 3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one 86499-96-9 C10H10BrNO
Zofenopril calcium Zofenopril calcium 81938-43-4 C22H25CaNO4S2
Mildronate Mildronate 76144-81-5 C6H14N2O2
2-Phenoxyethanol 2-Phenoxyethanol 122-99-6 C8H10O2
Ethylenediaminetetraacetic acid Ethylenediaminetetraacetic acid 60-00-4 C10H16N2O8
Trichloroacetic acid Trichloroacetic acid 76-03-9 C2HCl3O2
Entecavir hydrate Entecavir hydrate 209216-23-9 C12H17N5O4
Posaconazole Posaconazole 171228-49-2 C37H42F2N8O4
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