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Postion:Product Catalog >API>Blood System Drugs>Anticoagulant and Antiplatelet Drugs>Rivaroxaban
Rivaroxaban
  • Rivaroxaban
  • Rivaroxaban
  • Rivaroxaban
  • Rivaroxaban
  • Rivaroxaban

Rivaroxaban NEW

Price $220 $180 $120
Package 1KG 25KG 100KG
Min. Order: 1KG
Supply Ability: 20 tons
Update Time: 2024-04-10

Product Details

Product Name: Rivaroxaban CAS No.: 366789-02-8
EC-No.: 685-132-2 Min. Order: 1KG
Purity: USP/EP WC+DMF D90 < 10um Supply Ability: 20 tons
Release date: 2024/04/10

Product Information

Product name

Rivaroxaban

CAS No.

366789-02-8

Molecular Formula

C19H18ClN3O5S

Molecular Weight

435.8813

Quality Standard

98% up, Medicine Grade

Appearance

White powder


COA of Rivaroxaban

TEST

SPECIFICATION

RESULTS

Appearance

White to off-white powder

White powder

Identification

A: The infrared absorption of rivaroxaban corresponds to reference standards

Conforms


B: The retention time of the main peak of the sample solution corresponds to that of the system suitability solution, as obtained in the enantiomeric purity

Conforms 

ENANTIOMERIC PURITY

  RVX RC01: NMT 0.15%

None detected

WATER (KF)

NMT 0.5%

0.2%

SULPHATED ASH

NMT 0.1%

0.02%

ACETIC ACID

NMT 5000 ppm

774 ppm

RELATED SUBSTANCES(HPLC)

RVX RC02: NMT 0.15%

None detected

RVX RC03: NMT 0.15%

None detected

RVX RC04: NMT 0.15%

None detected

RVX RC05: NMT 0.15%

0.04 %

RVX RC06: NMT 0.15%

< disregard limit (0.03%)

RVX RC07: NMT 0.15%

None detected

RVX RC08: NMT 0.15%

None detected

Any other individual impurity: NMT 0.10%

0.07%

Total impurities: NMT 0.5%

0.15%

RESIDUAL SOLVENTS (GC)

Ethanol: NMT 5000 ppm

26 ppm

Toluene: NMT 890 ppm

None detected

Triethylamine: NMT 320 ppm

None detected

ASSAY

NLT 98.0% & NMT 102.0% (on anhydrous basis)

100.1%

STORAGE

Preserved in tight and light resistant container

Temperature:  30C

CONCLUSION

The product complies with the specification of In-house standard


Usage

Function of Rivaroxaban

Rivaroxaban is an oral, bioavailable factor Xa inhibitor that selectively blocks the active site of factor Xa and does not require cofactors (such as antithrombin III) to exert its activity. Factor X is activated by endogenous and exogenous pathways as factor Xa (FXa), which plays an important role in the coagulation cascade.


1. Rivaroxaban is for adult patients with elective hip or knee replacement surgery to prevent venous thrombosis (VTE).

2. Rivaroxaban is used to treat adult venous thrombosis (DVT) and reduce the risk of DVT recurrence and pulmonary embolism (PE) after acute DVT.

3. Rivaroxaban is for adult patients with non-valvular atrial fibrillation with one or more risk factors (for example: congestive heart failure, hypertension, age ≥75 years, history of diabetes, stroke or transient ischemic attack), to Reduce the risk of stroke and systemic embolism.

   In the condition of well-controlled treatment with warfarin, there are limited data on the relative effectiveness of rivaroxaban in reducing the risk of stroke and systemic embolism compared with warfarin.


Our advantages of Rivaroxaban (CAS:366789-02-8)  :
1. Quality: Form I,assay 98% up  ,conform to USP/EP standard , 

2. Normal PSD D90<100um & Micron PSD D90 <10um. 

3. Documents: local GMP,WC and DMF. CEP is under applying. The price with documents is higher than without.
4. Large capacity & stock : 120~180kg per month with 800kg in stock for prompt shipment
5. Better payment terms : We can make use of Export Credit Insurance after confirming yr credit report accepted by Sinosure, accept Alibaba Trade Assurance 
6. Various shipping ways for your choice : by air./ by sea / by courier (DHL/FedEx).


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Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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  • Since: 1996-07-16
  • Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.
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