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Postion:Product Catalog >API>Hormones and the Endocrine System>Prostaglandin drugs>Alprostadil
Alprostadil
  • Alprostadil
  • Alprostadil
  • Alprostadil
  • Alprostadil
  • Alprostadil

Alprostadil

Price Get Latest Price
Package 25Kg/Bag
Min. Order: 2Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-04-22

Product Details

Product Name: Alprostadil CAS No.: 745-65-3
Min. Order: 2Kg/Bag Purity: USP26 / 99% up
Supply Ability: 20 tons Release date: 2024/04/22

Product Information

Product name

Alprostadil

Molecular Formula

C20H34O5

Molecular Weight

354.48

CAS No.

745-65-3

Quality Standard

95% up, USP26

Appearance

White powder

COA of Alprostadil

Items

Specifications

Results

Appearance

White to off-white powder

Complies

Identification

HPLC retention time of sample complies with that of known sample

Complies

Water

≤0.5%

0.03%

Residual solvents

≤0.5%

0.02%

Residual on ignition

≤0.5%

0.20%

Related substances

PGAI:≤0.5%

Undetected

PGBI:≤0.5%

Undetected

13,14-Dihydro-PGEI: ≤0.5%

Undetected

Other impurities: ≤ 0.5%

Undetected

Assay

95.0%~105.0%

99.00%

Usage


Function of Alprostadil
Alprostadil, alias PGE1PGE1 is a biologically active substance widely present in the body, the mechanism of treating diabetic neuropathy:

1. Improve hemodynamics, increase the CAMP content in vascular smooth muscle cells, exert its vasodilator effect and reduce peripheral resistance;

2. To improve blood rheology, PGE can inhibit platelet aggregation, reduce platelet high response and thromboxane A (TXA) level, inhibit platelet activation, promote the reversal of activated platelets around thrombus, and improve the deformability of red blood cells;

3. PGE can activate lipoproteinase and promote triglyceride hydrolysis, reduce blood lipids and blood viscosity;

4. PGE can stimulate vascular endothelial cells to produce tissue-type fibrinolytic substance (t-PA), which has a certain direct thrombolytic effect.

5. By inhibiting free Caz of vascular smooth muscle cells and inhibiting the release of norepinephrine from vascular sympathetic nerve endings, the vascular smooth muscle is relaxed and the microcirculation is improved.


Article illustration



Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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