AZD3759 ,1626387-80-1 with high quality | China | Manufacturer | Shijiazhuang Tongyang Import and Export Co., LTD

Price	$50
Package	1KG

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Product Name: AZD3759	CAS No.: 1626387-80-1
Min. Order: 1KG	Purity: 99
Supply Ability: 20ton	Release date: 2021/08/07

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Product Name:	AZD 3759
Synonyms:	AZD 3759;AZD3759;AZD-3759;(2R)-2,4-Dimethyl-1-piperazinecarboxylic acid 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester;HY-18750;azd3579;1-Piperazinecarboxylic acid, 2,4-dimethyl-, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester, (2R)-;1-PIPERAZINECARBOXYLIC ACID, 2,4-DIMETHYL-, 4-[(3-CHLORO-2-FLUOROPHENYL)AMINO]-7-METHOXY-6-QUINAZOLINYL ESTER
CAS:	1626387-80-1
MF:	C22H23ClFN5O3
MW:	459.9
EINECS:	1592732-453-0
Product Categories:	API
Mol File:	1626387-80-1.mol

AZD 3759 Chemical PropertiesBoiling point 571.4±50.0 °C(Predicted)density 1.358±0.06 g/cm3(Predicted)pka6.71±0.40(Predicted)

Safety Information

MSDS Information

AZD 3759 Usage And SynthesisSelective EGFR inhibitor

AZD3759 is a selective EGFR inhibitor that can fully penetrate the blood-brain barrier (BBB), with equal free concentrations in the blood, cerebrospinal fluid, and brain tissue. Treatment with AZD3759 causes tumor regression in subcutaneous xenograft, leptomeningeal metastasis (LM), and brain metastasis (BM) lung cancer models and prevents the development of BM in nude mice.

DescriptionAZD3759 is an EGFP inhibitor (Epidermal growth factor receptor tyrosine kinase inhibitor) with blood brain barrier (BBB) penetration. It has the potential for the treatment of non-small cell lung cancer (NSCLC), with brain metastases (BM) and leptomengingeal metastases (LM) since this type of cancer often contain a lot of activating mutations of the epidermal growth factor receptor (EGFR). It has excellent capability of penetrating the blood brain barrier to reach the central nervous system

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Recommended supplier

Product name	Price		Suppliers	Update time
AZD3759	$0.00/1kg	VIP4Y	Hebei Yanxi Chemical Co., Ltd.	2023-10-09
AZD 3759	$100.00/25kg	VIP4Y	Hebei Mojin Biotechnology Co., Ltd	2022-07-04
AZD 3759	$0.00/1g		Wuhan Godbullraw Chemical Co.,ltd	2022-05-17
AZD 3759	$0.00/1KG		Wuhan Godbullraw Chemical Co.,ltd	2022-05-10
AZD3759	$10.00/1KG		Hebei Zhanyao Biotechnology Co. Ltd	2021-08-23
AZD3759	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-06-26
AZD3759	$0.00/20KG		Qiuxian Baitai New Material Co., LTD	2021-03-15
AZD 3759	$100.00/1ASSAYS		Handan Tongyi New Material Technology Co., Ltd	2021-03-09
AZD 3759	$7.00/1kg	VIP6Y	Career Henan Chemical Co	2018-12-22
AZD3759 Powder	$50.00/1g		Hebei Zhanyao Biotechnology Co. Ltd	2021-08-18

AZD3759

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Shijiazhuang Tongyang Import and Export Co., LTD