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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>Vonoprazan fumarate
Vonoprazan fumarate
  • Vonoprazan fumarate
  • Vonoprazan fumarate
  • Vonoprazan fumarate
  • Vonoprazan fumarate
  • Vonoprazan fumarate

Vonoprazan fumarate

Price $29.99
Package 1KG
Min. Order: 1KG
Supply Ability: 50ton
Update Time: 2021-09-02

Product Details

Product Name: Vonoprazan fumarate CAS No.: 1260141-27-2
EC-No.: 250-635-4 Min. Order: 1KG
Purity: 99% Supply Ability: 50ton
Release date: 2021/09/02

Physicochemical properties
Molecular formula: C21H20FN3O6S
Molecular weight: 461.463
Exact quality: 461.105682
PSA: 146.97000
LogP: 3.82910

Effect
1. Voronolazan fumarate (TAK-438) belongs to potassium ion (K+) competitive acid blocker (P-CAB), which is a reversible proton pump inhibitor. After this product enters the human body, it is in the stomach wall. The last step of cell acid secretion is to stop the secretion of gastric acid by inhibiting the combination of K+ and H+-K+-ATPase (proton pump) to achieve the acid suppression effect. This product has a strong and long-lasting effect of inhibiting gastric acid secretion.
2. AK-438 is a potassium-competitive acid blocker with oral activity. Its IC50 value for inhibiting H+ and K+-ATPase is 19 nM.

Article illustration

Company Profile Introduction

Aumei biotechnology co., LTD. Is located in wuhan, China, is a collection research and development, production, sales for the integration of medicine and chemical industry leader, the company has been to high-quality products and services to Chinese and foreign customers.

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  • Since: 2021-05-25
  • Address: Room H05106, Building 1, No.58 Optics Valley Avenue, East Lake New Technology Development Zone, Wuha
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