(1R,2R)-ML-SI3 NEW
| Price | $233 | $1110 | $1450 |
| Package | 2mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-23 |
Product Details
| Product Name: (1R,2R)-ML-SI3 | CAS No.: 2418594-00-8 |
| Supply Ability: 10g | Release date: 2025/06/23 |
Product Introduction
Bioactivity
| Name | (1R,2R)-ML-SI3 |
| Description | (1R,2R)-ML-SI3 ((-)-trans-ML-SI3) is a selective TRPML1, TRPML2, and TRPML3 inhibitor for the study of neurodegenerative and cardiovascular diseases. |
| In vitro | (1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of all three TRPML isoforms. (1R,2R)-ML-SI3 was a potent inhibitor of TRPML1 (IC50=1.6 μM), TRPML2 (IC50=2.3 μM) and TRPML3 (IC50=12.5 μM), (1R,2R)-ML-SI3 was a potent inhibitor of TRPML1 and TRPML2 and a weak inhibitor of TRPML3. [1] |
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 80 mg/mL(186.23 mM), Sonication is recommended. |
| Keywords | TRPML |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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