Product Details
| Product Name: 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid | CAS No.: 57078-98-5 |
| Min. Order: 1KG | Purity: 99%, 99.5% Sublimated |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2025/09/25 |
1. Materials information
Use of 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
4-Maleimidobutyric acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Description | 4-Maleimidobutyric acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker |
| Target | Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 400.1±28.0 °C at 760 mmHg |
| Melting Point | 95-98ºC |
| Molecular Formula | C8H9NO4 |
| Molecular Weight | 183.161 |
| Flash Point | 195.8±24.0 °C |
| Exact Mass | 183.053162 |
| PSA | 74.68000 |
| LogP | 0.40 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.553 |
| Storage condition | 2-8°C |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: elin@fdachem.com
Mob: 86 13613820652
WhatsApp/Skype/Wechat/LINE: 86 13613820652
Company Profile Introduction
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