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Postion:Product Catalog >Biochemical Engineering>Nucleoside drugs>Deoxynucleotides and their analogs>5-Chloro-2'-deoxyuridine
5-Chloro-2'-deoxyuridine
  • 5-Chloro-2'-deoxyuridine

5-Chloro-2'-deoxyuridine NEW

Price $30 $40
Package 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-11-04

Product Details

Product Name: 5-Chloro-2'-deoxyuridine CAS No.: 50-90-8
Purity: 99.54% Supply Ability: 10g
Release date: 2025/11/04

Product Introduction

Bioactivity

Name5-Chloro-2'-deoxyuridine
Description5-Chloro-2'-deoxyuridine (5-Chlorodeoxyuridine) is a thymine analog. It can be used to study the potential of hypochlorous acid damage to DNA and DNA precursors.
In vitroThe mammalian cells incorporate the analog into DNA when 5-Chloro-2’-deoxyuridine (ClDU) is placed into the tissue culture medium. It is observed that a 10 μM concentration of 5-Chloro-2’-deoxyuridine in the media does not alter cell division kinetics. Previously it has been shown that 5-Chloro-2’-deoxyuridine is metabolized and incorporated into DNA using antibodies that bind selectively to DNA containing halogenated bases. In this study, 5-Chloro-2’-deoxyuridine is more similar to BrdU in acting as a T analog. The toxicity of 5-Chloro-2’-deoxyuridine could in part be attributed to inhibition of thymidylate synthase [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (15.23 mM), Sonication is recommended.
DMSO : 125 mg/mL (475.92 mM), Sonication is recommended.
KeywordsInhibitor | inhibit | 5Chloro2'deoxyuridine | 5-Chloro-2'-deoxyuridine | 5 Chloro 2' deoxyuridine
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Nucleotide Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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