Nucleoside drugs

Many of the purine pyrimidine nucleoside analogues, which are promising antiviral compounds, are antiviral in tissue culture and in vivo. The compounds with selective inhibition of the virus, low toxicity, and effective in animals develop into nuclei Glycosides antiviral drugs. Currently, nucleoside drugs that are effective in clinical applications, have commodities, and have been recognized include iodine glycosides, trifluorothymidine, cyclosine, a sugar adenosine, acyclovir and so on. Nucleoside drugs that have a certain effect in clinical trials, have goods in some countries, yet to be recognized include ribavirin, arabinosyl adenosine monophosphate, bromide uridine and so on. Clinical trials are under way to observe the effect include fluoro-iodine cytosine. The new anti-viral nucleoside compounds have been reported is still in research and development. Nucleoside analogs are nucleic acid antimetabolites that are structurally analogous to nucleic acid precursors, competing for nucleic acid synthase enzyme systems, replacing normal nucleic acid precursors, or inhibiting nucleic acid synthetases, blocking viral or cellular nucleic acid synthesis, selectively inhibiting viral nucleic acids , while have little effect on the synthesis of nucleic acid.
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Structure Chemical Name CAS MF
ADP ADP 58-64-0 C10H15N5O10P2
2-Chloroadenosine 2-Chloroadenosine 146-77-0 C10H12ClN5O4
Thymidine Thymidine 50-89-5 C10H14N2O5
5-Chlorouracil 5-Chlorouracil 1820-81-1 C4H3ClN2O2
Cladribine Cladribine 4291-63-8 C10H12ClN5O3
Tetrazole Tetrazole 288-94-8 CH2N4
CYTIDINE 5'-DIPHOSPHOCHOLINE CYTIDINE 5'-DIPHOSPHOCHOLINE 987-78-0 C14H26N4O11P2
5-Azacytidine 5-Azacytidine 320-67-2 C8H12N4O5
Guanosine 5'-monophosphate disodium salt Guanosine 5'-monophosphate disodium salt 5550-12-9 C10H12N5Na2O8P
2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 84955-31-7 C6H5ClN4
5-Aza-2'-deoxycytidine 5-Aza-2'-deoxycytidine 2353-33-5 C8H12N4O4
6-Mercaptopurine monohydrate 6-Mercaptopurine monohydrate 6112-76-1 C5H6N4OS
6-Chloropurine riboside 6-Chloropurine riboside 2004-06-0 C10H11ClN4O4
2'-Deoxycytidine monohydrate 2'-Deoxycytidine monohydrate 951-77-9 C9H13N3O4
Mesitylene-2-sulfonyl chloride Mesitylene-2-sulfonyl chloride 773-64-8 C9H11ClO2S
Adenine sulphate Adenine sulphate 321-30-2 C10H12N10O4S
Cytidine Cytidine 65-46-3 C9H13N3O5
2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine 161599-46-8 C13H16FN3O6
2,6-Dihydroxypurine 2,6-Dihydroxypurine 69-89-6 C5H4N4O2
Dideoxyadenosine Dideoxyadenosine 4097-22-7 C10H13N5O2
Adenosine-5'-diphosphate disodium salt Adenosine-5'-diphosphate disodium salt 16178-48-6 C10H13N5Na2O10P2
2',3',5'-Tri-O-acetyluridine 2',3',5'-Tri-O-acetyluridine 4105-38-8 C15H18N2O9
Benzoic anhydride Benzoic anhydride 93-97-0 C14H10O3
5-Methyluridine 5-Methyluridine 1463-10-1 C10H14N2O6
Capecitabine Capecitabine 154361-50-9 C15H22FN3O6
5-Nitrouracil 5-Nitrouracil 611-08-5 C4H3N3O4
2,6-Diaminopurine 2,6-Diaminopurine 1904-98-9 C5H6N6
2',3'-O-Isopropylideneadenosine 2',3'-O-Isopropylideneadenosine 362-75-4 C13H17N5O4
2,6-Dichloropurine 2,6-Dichloropurine 5451-40-1 C5H2Cl2N4
6-Chloropurine 6-Chloropurine 87-42-3 C5H3ClN4
2-Amino-6-chloropurine-9-riboside 2-Amino-6-chloropurine-9-riboside 2004-07-1 C10H12ClN5O4
6-(Methylthio)purine 6-(Methylthio)purine 50-66-8 C6H6N4S
Disodium uridine-5'-monophosphate Disodium uridine-5'-monophosphate 3387-36-8 C9H11N2Na2O9P
ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT 149022-20-8 C10H12N5Na2O7P
1,2,4-Triazole 1,2,4-Triazole 288-88-0 C2H3N3
2,2'-Cyclouridine 2,2'-Cyclouridine 3736-77-4 C9H10N2O5
Zalcitabine Zalcitabine 7481-89-2 C9H13N3O3
4,6-Dihydroxy-2-methylpyrimidine 4,6-Dihydroxy-2-methylpyrimidine 40497-30-1 C5H6N2O2
2-Aminoadenosine 2-Aminoadenosine 2096-10-8 C10H14N6O4
Cytidylic acid Cytidylic acid 63-37-6 C9H14N3O8P
Guanosine Guanosine 118-00-3 C10H13N5O5
Broxuridine Broxuridine 59-14-3 C9H11BrN2O5
2'-Deoxyguanosine monohydrate 2'-Deoxyguanosine monohydrate 961-07-9 C10H15N5O5
1,2,3-1H-Triazole 1,2,3-1H-Triazole 288-36-8 C2H3N3
2,4-Dihydroxypyrimidine-5-carboxylic acid 2,4-Dihydroxypyrimidine-5-carboxylic acid 23945-44-0 C5H4N2O4
2'-Fluoro-2'-deoxyuridine 2'-Fluoro-2'-deoxyuridine 784-71-4 C9H11FN2O5
2'-Deoxyuridine 2'-Deoxyuridine 951-78-0 C9H12N2O5
Adenosine 5'-triphosphate disodium salt Adenosine 5'-triphosphate disodium salt 51963-61-2 C10H14N5Na2O13P3
5-Fluorouracil 5-Fluorouracil 51-21-8 C4H3FN2O2
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 10212-20-1 C9H12FN3O4
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine 3680-69-1 C6H4ClN3
5-Fluorocytidine 5-Fluorocytidine 2341-22-2 C9H12FN3O5
Adenosine 5'-monophosphate Adenosine 5'-monophosphate 61-19-8 C10H14N5O7P
2'-Deoxyadenosine monohydrate 2'-Deoxyadenosine monohydrate 16373-93-6 C10H13N5O3
5'-Deoxy-5-fluorocytidine 5'-Deoxy-5-fluorocytidine 66335-38-4 C9H12FN3O4
5-CARBETHOXYURACIL 5-CARBETHOXYURACIL 28485-17-8 C7H8N2O4
2,6-Dichloropurine riboside 2,6-Dichloropurine riboside 13276-52-3 C10H10Cl2N4O4
5-Methyl-2'-deoxycytidine 5-Methyl-2'-deoxycytidine 838-07-3 C10H15N3O4
Nicotinamide riboside chloride Nicotinamide riboside chloride 23111-00-4 C11H15ClN2O5
5-Bromouridine 5-Bromouridine 957-75-5 C9H11BrN2O6
DIBENZYL DIISOPROPYLPHOSPHORAMIDITE DIBENZYL DIISOPROPYLPHOSPHORAMIDITE 108549-23-1 C20H28NO2P
Cordycepin Cordycepin 73-03-0 C10H13N5O3
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione 666816-98-4 C10H9BrN4O2
5-Nitroso-2,4,6-triaminopyrimidine 5-Nitroso-2,4,6-triaminopyrimidine 1006-23-1 C4H6N6O
2',3'-O-Isopropylideneinosine 2',3'-O-Isopropylideneinosine 2140-11-6 C13H16N4O5
5-Ethyluracil 5-Ethyluracil 4212-49-1 C6H8N2O2
Nucleoside Nucleoside
4-Amino-3-hydrazino-1,2,4-triazol-5-thiol 4-Amino-3-hydrazino-1,2,4-triazol-5-thiol 1750-12-5 C2H6N6S
6-AZATHYMINE 6-AZATHYMINE 932-53-6 C4H5N3O2
N4-Benzoylcytosine N4-Benzoylcytosine 26661-13-2 C11H9N3O2
6-Chloroguanine 6-Chloroguanine 10310-21-1 C5H4ClN5
Ethyl tetrazole-5-carboxylate Ethyl tetrazole-5-carboxylate 55408-10-1 C4H6N4O2
N4-Acetylcytosine N4-Acetylcytosine 14631-20-0 C6H7N3O2
5-Iodo-2,4-dimethoxypyrimidine 5-Iodo-2,4-dimethoxypyrimidine 52522-99-3 C6H7IN2O2
N,9-Diacetylguanine N,9-Diacetylguanine 3056-33-5 C9H9N5O3
CTP CTP 65-47-4 C9H16N3O14P3
2,6-Dihydroxy-3-methylpurine 2,6-Dihydroxy-3-methylpurine 1076-22-8 C6H6N4O2
Guanine hydrochloride Guanine hydrochloride 635-39-2 C5H6ClN5O
2'-Deoxyinosine 2'-Deoxyinosine 890-38-0 C10H12N4O4
Purine Purine 120-73-0 C5H4N4
N-Benzoylaminopurine N-Benzoylaminopurine 4005-49-6 C12H9N5O
Adenosine 5'-monophosphate disodium salt Adenosine 5'-monophosphate disodium salt 4578-31-8 C10H12N5Na2O7P
2'-O-Methyluridine 2'-O-Methyluridine 2140-76-3 C10H14N2O6
N4-Benzoylcytidine N4-Benzoylcytidine 13089-48-0 C16H17N3O6
Uridine-5'-triphosphoric acid trisodium salt Uridine-5'-triphosphoric acid trisodium salt 19817-92-6 C9H12N2Na3O15P3
2'-Deoxycytidine hydrochloride 2'-Deoxycytidine hydrochloride 3992-42-5 C9H14ClN3O4
6-Hydrazinopurine 6-Hydrazinopurine 5404-86-4 C5H6N6
Thymidine-5'-monophosphate disodium salt Thymidine-5'-monophosphate disodium salt 33430-62-5 C10H13N2Na2O8P
Deoxyribonucleoside Deoxyribonucleoside
2'-O-Methylcytidine 2'-O-Methylcytidine 2140-72-9 C10H15N3O5
2',3',5'-Triacetylguanosine 2',3',5'-Triacetylguanosine 6979-94-8 C16H19N5O8
Isocytosine Isocytosine 108-53-2 C4H5N3O
5-Amino-4,6-dichloro-2-methylpyrimidine 5-Amino-4,6-dichloro-2-methylpyrimidine 39906-04-2 C5H5Cl2N3
2-Amino-6-iodopurine 2-Amino-6-iodopurine 19690-23-4 C5H4IN5
1-(2,4,6-Triisopropylphenylsulfonyl)imidazole 1-(2,4,6-Triisopropylphenylsulfonyl)imidazole 50257-40-4 C18H26N2O2S
URIC ACID URIC ACID 69-93-2 C5H4N4O3
Adenine hydrochloride hemihydrate Adenine hydrochloride hemihydrate 6055-72-7 C5H8ClN5O
2'-Deoxyadenosine 5'-phosphate 2'-Deoxyadenosine 5'-phosphate 653-63-4 C10H14N5O6P
5'-O-Dimethoxytrityl-deoxythymidine 5'-O-Dimethoxytrityl-deoxythymidine 40615-39-2 C31H32N2O7
2-Fluoroadenine 2-Fluoroadenine 700-49-2 C5H4FN5
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