Pazufloxacin

Price	$2
Package	1kg

Product Details

Product Name: Pazufloxacin	CAS No.: 127045-41-4
Min. Order: 1kg	Purity: 98%
Supply Ability: 100kg	Release date: 2019/07/06
Product Number:: wm1024

Pazufloxacin Basic information

Description References

Product Name:	Pazufloxacin
Synonyms:	PAZUFLOXAXIN;T-3761;(s)-yclopropyl)-9-fluoro-3-methyl-7-oxo;Pazufloxacinmyesylate;(3S)-10-(1-AMINOCYCLOPROPYL)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID;ALKALYL;Pazufloxaxin mesilate;PAZUFLOXACIN 98+%
CAS:	127045-41-4
MF:	C16H15FN2O4
MW:	318.3
EINECS:	1806241-263-5
Product Categories:	BacteriostaticAntibiotics;ChinolonesAlphabetic;PA - PENAnalytical Standards;Pharmacology Standards;Antibiotics;Chemical Structure;Chromatography;P;Principle;API's
Mol File:	127045-41-4.mol

Pazufloxacin Chemical Properties

Melting point	269-271°C
alpha	D25 -88.0° (c = 0.5 in 0.05N aq NaOH)
density	1.56
storage temp.	2-8°C
CAS DataBase Reference	127045-41-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,C,F
Risk Statements	20/21/22-34-11
Safety Statements	36/37-45-36/37/39-26-16
RTECS	UU8815300
Toxicity	LD50 i.v. in male mice: >500 mg/kg (Todo)

MSDS Information

Provider	Language
(3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid	English

Pazufloxacin Usage And Synthesis

Description	Pazufloxacin is a fluoroquinolone with a 1-aminocyclopropyl substituent at C10 position. The presence of aminoacyl group at C-10 is a unique feature of the molecule imparting potent broad spectrum activity against gram-positive and gram-negative bacteria. This activity is based on the inhibition of bacterial DNA gyrase. Pazufloxacin is used as an injectable antibiotic with bacterial effect against cephalosporin-resistant, carbapenem-resistance, and aminoglycoside resistant strains of bacteria. The adverse effects of pazufloxacin, such as drug-induced convulsion and hypotension are less than those of other conventional injectable fluoroquinolones.
References	[1] A. Vora, Pazufloxacin, tracked from www.japi.org on 16.07.2017 [2] Jeffrey K. Aronson, Meyler’s Side Effects of Antimicrobial Drugs, 2009 [3] Satoshi Watabe, Yoshiaki Yokoyama, Kazuyuki Nakazawa, Kimikazu Shinozaki, Rika Hiraoka, Kei Takeshita and Yukio Suzuki, Simultaneous measurement of pazufloxacin, ciprofloxacin, and levofloxacin in human serum by high-performance liquid chromatography with fluorescence detection, Journal of Chromatography B, 2010, vol. 878, 1555-1561
Uses	antibactierial

Pazufloxacin Preparation Products And Raw materials

Raw materials

Ethyl acetate-->Trifluoroacetic acid-->Sodium sulfite-->Sodium azide-->Paraformaldehyde-->N,N-Dimethylformamide dimethyl acetal-->Dimethyl sulfide-->Methanesulfonic acid-->1,1'-Carbonyldiimidazole-->5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide-->Diphenyldiazomethane-->Ethyl 2,3,4,5-tetrafluorobenzoate-->Di-tert-Butyl malonate

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

Recommended supplier

Product name	Price		Suppliers	Update time
Pazufloxacin	$0.00/1KG	VIP2Y	Hebei Guanlang Biotechnology Co., Ltd.	2022-09-30
Pazufloxacin	$0.00/10mg		Guangzhou PI PI BIOTECH INC	2022-04-15
Pazufloxacin USP/EP/BP	$1.10/1g	VIP3Y	Dideu Industries Group Limited	2021-07-19
Pazufloxacin	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-07-10
Pazufloxacin	$0.01/1KG	VIP5Y	Shaanxi Dideu Medichem Co. Ltd	2020-05-12
Pazufloxacin	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-07-09
Pazufloxacin	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-06-27

Product Details

Company Profile Introduction

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Recommended supplier

career henan chemical co