6-CHLORO-5-NITROPYRIMIDIN-4-AMINE NEW
| Price | Get Latest Price |
| Package | 200kg |
| Min. Order: | 100kg |
| Supply Ability: | 20 tons |
| Update Time: | 2025-04-02 |
Product Details
| Product Name: 6-CHLORO-5-NITROPYRIMIDIN-4-AMINE | CAS No.: 4316-94-3 |
| Min. Order: 100kg | Purity: 0.99 |
| Supply Ability: 20 tons | Release date: 2025/04/02 |
4-Amino-5-Nitro-6-Chloropyrimidine CAS 4316-94-3 | Core Supplier of High-Activity Nitropyrimidine Intermediates
Product Basic Information
Chemical Name: 4-Amino-5-nitro-6-chloropyrimidine
CAS Number: 4316-94-3 (Highlighted as a Title-Level Keyword)
Molecular Formula: C4H3ClN4O2
Appearance: Pale Yellow to Yellow Crystalline Powder
Purity: ≥98.0% (HPLC, Pharmaceutical Intermediate Grade)
Key Physical and Chemical Properties (Structured Data Optimized)
| Property | Parameter Value |
|---|---|
| Molecular Weight | 174.55 g/mol |
| Melting Point | 215-218°C (Decomposition) |
| Density (25°C) | 1.72 g/cm³ |
| Solubility | Soluble in DMSO, DMF; Slightly soluble in Ethanol; Insoluble in Water |
| Stability | Light-sensitive, Stable at pH 4-9 |
| Storage Conditions | Sealed and Protected from Light, Store at -20°C in a Dry Place |
| Hygroscopicity | ≤0.5% (25°C/60% RH) |
Upstream and Downstream Industry Chain Integration
▶ Upstream Raw Material Guarantee
Core Intermediates: 4,6-Dichloropyrimidine, Potassium Nitrate/Nitration Reagent
Process Optimization: Stepwise Nitration-Amination Technology (Overall Yield >80%, Impurities <0.5%)
▶ Downstream Application Expansion
Anticancer Drugs: Key Precursor for Thymidylate Synthase Inhibitors
Agricultural Fungicides: Modification of Molecular Skeleton of Pyrimidine Ester Compounds
Optoelectronic Materials: Synthesis of Organic Semiconductor Dopants
Molecular Probes: Development of DNA/RNA Base Analogues
Industry Solutions and Technical Advantages
| Application Area | Typical Scenario | Technical Advantages |
|---|---|---|
| Anticancer Drugs | Structural Optimization of 5-Fluorouracil Derivatives | Amino-Directed Acylation Yield >93% (HPLC Verified) |
| Agrochemicals | Synthesis of Methoxyacrylate Fungicides | Hydrolysis Resistance (Stability >90% at pH 5-8) |
| OLED Materials | Preparation of Hole-Blocking Materials for Electron Transport Layers | Purity ≥99.9% (Gradient Sublimation Process) |
| Chemical Biology | Base Modification Markers for Nucleic Acid Drugs | Nitro Reduction Reaction Selectivity >95% |
SEO Keyword Matrix
Core Keyword Layout:
"4-Amino-5-nitro-6-chloropyrimidine Price"
"CAS 4316-94-3 Technical Parameters"
"High-Activity Nitropyrimidine Supplier"
Long-Tail Keyword Combinations:
"Custom Synthesis of Anticancer Drug Intermediates"
"Manufacturer of Raw Materials for Pyrimidine Ester Fungicides"
"Pharmaceutical Grade 4316-94-3 Producer"
Quality System and Service Commitment
✅ cGMP Compliant Production: Complies with ICH Q7 Standards for Active Pharmaceutical Ingredient Starting Materials
✅ Customized Services: Supports Orders from Gram to Hundred-Kilogram Levels (MOQ 50g)
✅ Analysis Report: Provides Full Documentation Including HPLC, 1H NMR, and Elemental Analysis
✅ Global Logistics: UN 3077 Certified Packaging (Moisture-Proof Aluminum Foil Bags + Desiccant)



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- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China

China