AM 630;6-IODO-2-METHYL-1-[[2-(4-MORPHOLINYL)ETHYL]-1H-INDOL-3-YL](4-METHOXYPHENYL)METHANONE

Product Name:

AM 630

Synonyms:

AM 630;6-IODO-2-METHYL-1-[[2-(4-MORPHOLINYL)ETHYL]-1H-INDOL-3-YL](4-METHOXYPHENYL)METHANONE;SC-200365(AM-630);1-[2-(Morpholin-4-yl)ethyl]-2-Methyl-3-(4-Methoxybenzoyl)-6-iodoindole;(6-iodo-2-Methyl-1-(2-Morpholinoethyl)-1H-indol-3-yl)(4-Methoxyphenyl)Methanone;Methanone, [6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)-;Iodopravadoline (AM630)

CAS:

MF:

C23H25IN2O3

MW:

504.36

EINECS:

 

Product Categories:

Cannabinoid receptor

Mol File:

164178-33-0.mol

 

AM 630 Chemical Properties

storage temp. 

Desiccate at +4°C

solubility 

DMSO: >5mg/mL

form 

powder

color 

white to beige

 

Safety Information

Hazard Codes 

N

Risk Statements 

50

Safety Statements 

61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

MSDS Information

 

AM 630 Usage And Synthesis

Uses

AM 630 acts as a potential CB2 receptor cannabinoid antagonist with application towards human lung cancer treatment and angiogenesis induction.

Biological Activity

CB 2 antagonist/inverse agonist (K i = 31.2 nM) that displays 165-fold selectivity over CB 1 receptors. Behaves as a weak partial/inverse agonist at CB 1 receptors.