LY-364947
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20kg |
| Update Time: | 2019-09-06 |
Product Details
| Product Name: LY-364947 | CAS No.: 396129-53-6 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: 20kg | Release date: 2019/09/06 |
Abby020
▼
▲
▼
▲
▼
▲
LY-364947 Basic information
▼
▲
Product Name:
LY-364947
Synonyms:
LY-364947;[3-(Pyridin-2-yl)-4-(4-quinonyl)]-1H-pyrazole;4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-quinoline;LY364947(HTS 466284);E 616451;HTS 466284;2-[4-(Quinolin-4-yl)-1H-pyrazol-3-yl]pyridine, 3-(Pyridin-2-yl)-4-(quinolin-4-yl)-1H-pyrazole;Quinoline, 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-
CAS:
396129-53-6
MF:
C17H12N4
MW:
272.31
EINECS:
Product Categories:
API;Inhibitors;Smad;TGF-beta
Mol File:
396129-53-6.mol
▼
▲
LY-364947 Chemical Properties
▼
▲
Melting point
>230℃ (dec.)
storage temp.
Store at RT
solubility
DMSO: soluble2mg/mL, clear
form
powder
color
white to beige
InChIKey
IBCXZJCWDGCXQT-UHFFFAOYSA-N
▼
▲
Safety Information
▼
▲
Hazard Codes
T,N
Risk Statements
25-36/37/38-50/53
Safety Statements
26-45-60-61
RIDADR
UN 2811 6.1/PG 3
WGK Germany
3
▼
▲
MSDS Information
▼
▲
LY-364947 Usage And Synthesis
▼
▲
Biological Activity
Selective inhibitor of TGF- β type-I receptor (TGF- β RI, TGFR-I, T β R-I, ALK-5) (IC 50 values are 59, 400 and 1400 nM for TGR- β RI, TGF- β RII and MLK-7K respectively). Inhibits TGF- β -dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3) (IC 50 values are 47 and 89 nM respectively). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay.
▼
▲
LY-364947 Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
You may like
-
-
-
CAS:1420071-30-2
$1.00 / 1KG
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/1g |
VIP3Y
|
Wuhan Nutra Biotechnology Co.,Ltd
|
2021-05-24 | |
| $200.00/1KG |
VIP1Y
|
Henan Fengda Chemical Co., Ltd
|
2024-01-02 | |
| $50.00/1kg |
Anhui Ruihan Technology Co., Ltd
|
2023-09-08 | ||
| $30.00/2mg |
VIP2Y
|
Zhuzhou New Peptides Tech Co.,Ltd.
|
2023-08-02 |
China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
杨俊青
15093356674
sales@coreychem.com
15093356674
sales@coreychem.com