7-Diethylamino-4-methylcoumarin NEW

7-Diethylamino-4-methylcoumarin (DEAMC)

Key Properties

Core Uses Across Industries

1. Fluorescence Imaging & Analytical Chemistry

• Fluorescent Probe: Widely used as a fluorescent label for biomolecules (proteins, nucleic acids, antibodies) in fluorescence microscopy, flow cytometry, and immunoassays (e.g., ELISA). Its blue fluorescence minimizes background interference, enabling high-sensitivity detection of target analytes.

• Analytical Reagent: Used in spectrofluorometry to detect metal ions (e.g., Fe³⁺, Cu²⁺) and small molecules (e.g., amines, thiols) via fluorescence quenching or enhancement. It is also a standard reference material for calibrating fluorescence instruments.

2. Optical Materials & Photonics

• Laser Dyes: Employed as an active medium in dye lasers, emitting blue-green light for applications in spectroscopy, medical imaging, and laser printing.

• Optical Brighteners: Added to polymers (plastics, fibers) and coatings to enhance whiteness and UV resistance, leveraging its fluorescence to mask yellowing.

• Organic Electronics: Used in the fabrication of organic light-emitting diodes (OLEDs) and fluorescent sensors due to its efficient light-emitting properties and charge-transport capability.

3. Pharmaceutical & Biomedical Research

• Drug Discovery: Serves as a scaffold for synthesizing bioactive compounds (e.g., anticoagulants, antimicrobial agents) due to the coumarin core’s pharmacological activity.

• Biomedical Imaging: Conjugated with targeting ligands (e.g., peptides, aptamers) for in vitro/in vivo imaging of cancer cells, bacteria, or biological tissues, aiding in disease diagnosis and treatment monitoring.

4. Industrial & Consumer Products

• UV Absorbers: Incorporated into sunscreens, cosmetics, and plastics to absorb UV radiation (280–380 nm), preventing photo-degradation and skin damage.

• Fluorescent Markers: Used in security inks (banknotes, documents) and textile printing for anti-counterfeiting purposes, as its fluorescence is visible only under UV light.

Safety & Handling

• Low acute toxicity, but prolonged skin contact may cause mild irritation; wear protective gloves and goggles during handling.

• Avoid exposure to strong oxidizing agents and UV radiation (to prevent fluorescence quenching).

• Store in a sealed container away from heat and light to maintain stability.

Commercial Significance