Ionomycin NEW
| Price | $196 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2026-01-21 |
Product Details
| Product Name: Ionomycin | CAS No.: 56092-81-0 |
| Purity: 99.54% | Supply Ability: 10g |
| Release date: 2026/01/21 |
Product Introduction
Bioactivity
| Name | Ionomycin |
| Description | Ionomycin is a calcium ion carrier and an antibiotic that binds to calcium ions (Ca2+). The main function of Ionomycin is to induce cellular responses by increasing the intracellular calcium ion concentration. In experiments, Ionomycin is typically used to activate calcium-dependent processes, such as apoptosis and enzyme activity. |
| In vitro | METHODS: LCLC 103H cells were treated with Ionomycin and analyzed using DNA and protein. RESULTS: Ionomycin induces DNA fragmentation and PARP lysis into an 85-kDa fragment of typical caspase-mediated apoptosis. [1] |
| In vivo | METHODS: To investigate the activation of immune cells by Ionomycin, PMA and Ionomycin were used to activate CD4+CD25- T cells in mice to generate inductive regulatory T cells (iTreg), and their functions were tested in a mouse model of inflammatory bowel disease (IBD). RESULTS: iTreg cells activated by Ionomycin could significantly alleviate the symptoms of IBD mouse models, including weight loss and reduced disease activity scores. [2] METHODS: To study the role of calcium signaling in embryonic development, Ionomycin was added to the mouse embryo culture medium. RESULTS: Calcium signaling plays a key role in embryonic cell migration and morphogenesis. [3] |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 90 mg/mL (126.94 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (4.65 mM), Sonication is recommended. DMSO : 90 mg/mL (126.94 mM), Sonication is recommended. |
| Keywords | Ionomycin | CalciumChannel | Calcium ionophore | Calcium Channel |
| Inhibitors Related | Neomycin sulfate | Aceglutamide | 2,4,6-Tri-tert-butylphenol | Tamoxifen | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Dimethyl sulfoxide | Sodium diacetate | BES |
| Related Compound Libraries | Rare Natural Product Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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