Anipamil NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-22 |
Product Details
| Product Name: Anipamil | CAS No.: 83200-10-6 |
| Supply Ability: 10g | Release date: 2025/08/22 |
Product Introduction
Bioactivity
| Name | Anipamil |
| Description | Anipamil is a long-acting blocker of calcium channel,and for the treatment of cardiovascular disease. |
| In vivo | Anipamil effectively suppresses the proliferation of smooth muscle cells (SMC), promoting a more differentiated phenotype characterized by the expression of smooth muscle myosin heavy chain (SM-MyHC) compared to untreated controls. In 2K-1C rabbits, oral administration of anipamil (40 mg) significantly reduces or eliminates intimal thickening and decreases the presence of immature SMC types in the media layer. Furthermore, renal function protection is notably enhanced in anipamil (2 mg/kg/day)-treated groups compared with those receiving hydralazine, achieving equivalent blood pressure management. Anipamil also demonstrates efficacy in arrhythmic assays, specifically reducing ventricular tachycardia (VT) at doses of 1.0 mg/kg + 0.10 mg/kg/min or 5.0 mg/kg + 0.50 mg/kg/min, although ventricular fibrillation (VF) remains unaffected. In rats undergoing substantial nephrectomy (five-sixths removed) and treated with anipamil (0.5 mg/kg/day, orally), outcomes are improved, showing lower mortality, better-managed mean arterial blood pressure, and reduced serum creatinine levels compared to controls. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Anipamil |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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