Baclofen NEW

English name: Baclofen

CAS number: 1134-47-0
Molecular formula: C10H12ClNO2
Molecular weight: 213.66
EINECS number: 214-486-9
MDL No. : MFCD00055143
Stats
Melting point 208-210°C
Boiling point 364.3±32.0 °C(Predicted)
Density 1.2069 (rough estimate)
Refractive index 1.5500 (estimate)
Storage conditions 2-8°C
Solubility 1 M HCl: 50 mg/mL
Acidity coefficient (pKa)pKa 3.87±0.1(H2O) (Uncertain)
Form solid
The color is white to very faintly yellow
Soluble in dilute NaOH or dilute HCl. Soluble in water at approximately 4mg/ml at pH 7.6. Soluble in dilute naoh or dilute HCL. Soluble in water at approximately 4mg/ mL at pH 7.6
Merck14, 937
Stability Hygroscopic
InChIInChI = 1 s/C10H12ClNO2 / c11-9-3-1-7 (2-4-9) 8 (6-12) 5-10 (13) 14 / h1-4, 8 H, 5-6, 12 H2, H., 13, 14)
InChIKeyKPYSYYIEGFHWSV-UHFFFAOYSA-N
SMILESC1(C=CC(Cl)=CC=1)C(CN)CC(=O)O
Safety information

1. Product Description:

Chemical properties: 

White powder. Melting point 206-208℃. Soluble in hot water, its aqueous solution is neutral, almost insoluble in ethanol, ether, acetone and other organic solvents, easily soluble in acidic and alkaline aqueous solutions. The melting point of chlorophenyl butyrate hydrochloride is 179-181℃.

Production method: 

Condensation of p-chlorobenzaldehyde with ethyl acetoacetate to form p-chlorobenzene - di-ethyl acetoacetate. Heated water hydrolyzes to p-chlorophenylglutaric acid. Hydrochlorophenylglutaric anhydride is formed by dehydration cyclization of acetic anhydride. Then it is aminated by concentrated ammonia water to form a chlorophenylglutaric acid imide, and finally ring-opening and degradation to p-chlorophenylaminocasic acid. The specific operation method of the final ring opening and degradation is as follows: 42.25gβ- (p-chlorophenyl) glutaric acid imide is added to 200ml aqueous solution containing 8.32g sodium hydroxide under stirring. The mixture was heated at 50℃ for 10min, cooled to 10-15℃, then added 200ml aqueous solution containing 40.9g sodium hydroxide, after 20min, added 38.8g bromine, stirred at 20-25℃ for 8h, carefully adjusted the pH value of the reaction solution with concentrated hydrochloric acid to 7, and then precipitated fine β-(p-chlorophenyl) -γ-amino-butyric acid crystals. Then recrystallized from water, melting point 206-208℃.

2. Basic Info.

3. Detailed Photo

4.Our advantages:

1) Timely communication, reply within 12 hours.You can leave any messages on our whatsapp or send email to us.

2)Selecting raw materials strictly,our products are the highest purity.

3)Reasonable and competitive price.

4) Free sample for your evaluation.Customers only need to undertake the shipping fee for delivery the samples to your destionation.

5)OEM/ODM Available.Trial order is available for testing after samples.

6) Packaging can be customized according to each buyers' special request.

We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

5.Company Introduction

  hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

6.After Sales Service

 1) Best quality in your requirement

 2)Competitive price in china market

 3)Mature technical support

 4)Professional logistic support

 5 )Full experience of large numberscontainers loading in chinese sea port

 6 )Fast shipment by reputed shipping line

 7) Packing with pallet as buyer's special request

 8) Best service after shipment.

 9) Cargoes together with container after-sales service available

 10) Full experience in export

 11)Raw materials from chinese origin                                                                  

7. FAQ

What is the way you ship?

Express: FedEx, UPS, EMS, DHL, USPS, TNT, DPD, Aramex etc

Our way of shipping the products is universal and secure.

The company name and other contents related to pharmacy are not written on the package slips.

The way of packing is regularly changed for a secure delivery.

The packages are small in order to avoid unwelcomed questions . If the order is big, then it will be divided into two or more packages

Can the packages be trackable?

YES, we provide tracking number and you can track on internet.

Where do you ship to?

Worldwide.

Do you offer domestic shipping/remail shipping?

Yes we can ship to USA/UK/Canada/Australia/Germany etc warehouse first then to you.

Do you ensure your packing , what about customs, what happens if the package is retained?

We concern a lot about our safety system, we pack the orders as secure as possible. If a package is seized at customs, reships of seized orders will be done provided you have a copy of the letter to show us. If you receive a seizure letter, please contact us immediately with a scanned copy of the seizure letter, and also a new address to have your order reshipped to.

Which payment options are available?

Bitcoin

Western Union

Bank wire

MoneyGram