D-Biotin NEW

Price	$6	$0.2
Package	1KG	1000KG

Min. Order:	1KG
Supply Ability:	g-kg-tons, free sample is available
Update Time:	2024-03-29

Product Details

Product Name: D-Biotin	CAS No.: 58-85-5
Min. Order: 1KG	Purity: 99%
Supply Ability: g-kg-tons, free sample is available	Release date: 2024/03/29
Lead time: In stock, ready for shipment	Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea	Origin: Manufacturer, advantage product
COA, MSDS: Available, contact us for details	Name: Tina

1. Materials information

Name	biotin
Synonym	More Synonyms

Description	Biotin is a water-soluble, enzyme co-factor present in minute amounts in every living cell.Target: OthersBiotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the citric acid cycle, which is the process by which biochemical energy is generated during aerobic respiration. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. In addition, biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. The dietary biotin intake in Western populations has been estimated to be 35 to 70 microg/d (143-287 nmol/d). Recent studies suggest that humans absorb biotin nearly completely. Conditions that may increase biotin requirements in humans include pregnancy, lactation, and therapy with anticonvulsants or lipoic acid [1, 2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Natural Products >> Others
References	[1]. Zempleni, J. and D.M. Mock, Biotin biochemistry and human requirements. J Nutr Biochem, 1999. 10(3): p. 128-38. [2]. Mock, D.M., Biotin status: which are valid indicators and how do we know? J Nutr, 1999. 129(2S Suppl): p. 498S-503S.

Description

Biotin is a water-soluble, enzyme co-factor present in minute amounts in every living cell.Target: OthersBiotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the citric acid cycle, which is the process by which biochemical energy is generated during aerobic respiration. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. In addition, biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. The dietary biotin intake in Western populations has been estimated to be 35 to 70 microg/d (143-287 nmol/d). Recent studies suggest that humans absorb biotin nearly completely. Conditions that may increase biotin requirements in humans include pregnancy, lactation, and therapy with anticonvulsants or lipoic acid [1, 2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Natural Products >> Others

References

[1]. Zempleni, J. and D.M. Mock, Biotin biochemistry and human requirements. J Nutr Biochem, 1999. 10(3): p. 128-38.

[2]. Mock, D.M., Biotin status: which are valid indicators and how do we know? J Nutr, 1999. 129(2S Suppl): p. 498S-503S.

Density	1.6±0.1 g/cm3
Boiling Point	492.3±55.0 °C at 760 mmHg
Melting Point	231-233 °C(lit.)
Molecular Formula	C10H16N2O3S
Molecular Weight	244.311
Flash Point	251.5±31.5 °C
Exact Mass	244.088165
PSA	103.73000
LogP	0.03
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.717

D-Biotin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ9088200

CHEMICAL NAME :
1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS-(3a-alpha,4-beta, 6a-alpha))-

CAS REGISTRY NUMBER :
58-85-5

LAST UPDATED :
199706

DATA ITEMS CITED :
7

MOLECULAR FORMULA :
C10-H16-N2-O3-S

MOLECULAR WEIGHT :
244.34

WISWESSER LINE NOTATION :
T55 BMVM GSTJ H4VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Subcutaneous

DOSE :
200 mg/kg

SEX/DURATION :
female 14-15 day(s) after conception

TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :
JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 22,181,1976

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Subcutaneous

DOSE :
100 mg/kg

SEX/DURATION :
male 1 day(s) pre-mating

TOXIC EFFECTS :
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :
CUSCAM Current Science. (Current Science Assoc., Sadashivanagar P.O., Bangalore 560 080, India) V.1- 1932- Volume(issue)/page/year: 42,613,1973

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Subcutaneous

DOSE :
200 mg/kg

SEX/DURATION :
female 1-2 day(s) after conception

TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :
JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 21,89,1975

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
17 mg/kg

SEX/DURATION :
female 1-17 day(s) after conception

TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects

REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 52,149,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80381 No. of Facilities: 129 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 8306 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80381 No. of Facilities: 1674 (estimated) No. of Industries: 9 No. of Occupations: 41 No. of Employees: 46583 (estimated) No. of Female Employees: 22672 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Risk Phrases	20/21/22-36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	XJ9088200
HS Code	29362930

cis-(-)-1,3-Dib...

33607-60-2

~93%

D-Biotin

58-85-5

Literature: DSM IP ASSETS B.V.; FUDAN UNIVERSITY Patent: WO2009/49476 A1, 2009 ; Location in patent: Page/Page column 38-39 ;

(3aS,4S,6aR)-5-...

292151-19-0

~90%

D-Biotin

58-85-5

Literature: DSM IP ASSETS B.V.; FUDAN UNIVERSITY Patent: WO2009/49476 A1, 2009 ; Location in patent: Page/Page column 39-40 ;

(3aS,4S,6aR)-1,...

31099-31-7

~95%

D-Biotin

58-85-5

Literature: DSM IP ASSETS B.V.; FUDAN UNIVERSITY Patent: WO2009/49476 A1, 2009 ; Location in patent: Page/Page column 39 ;

Precursor 5	Previous 1/2 Next
CAS#:292151-19-0 (3aS,4S,6aR)-5-... CAS#:31099-31-7 (3aS,4S,6aR)-1,... CAS#:83541-80-4 [3aS-(3aα,4β,6a... CAS#:24459-54-9 N,N'-dibenzylbi...
DownStream 9	Previous 1/3 Next
CAS#:33755-53-2 (+)-Biotin-ONP CAS#:576-19-2 Biocytin CAS#:35013-72-0 Biotin NHS CAS#:359860-27-8 Amine-PEG3-Biotin

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2. Packaging of materials

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

Article illustration

3. Shipping & Delivery

By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

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By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

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By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration

4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 15225627621

WhatsApp/Skype/Wechat/LINE: 86 15225627621

Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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