Dibucaine hydrochloride NEW
Price | Get Latest Price |
Package | 1g |
Min. Order: | 1g |
Supply Ability: | 1kg |
Update Time: | 2024-03-12 |
Product Details
Product Name: Dibucaine hydrochloride | CAS No.: 61-12-1 |
Min. Order: 1g | Purity: 98% HPLC |
Supply Ability: 1kg | Release date: 2024/03/12 |
Dibucaine hydrochloride (dibucaine hydrochloride) is a sodium channel inhibitor. Dibucaine hydrochloride is a potent SChE inhibitor。
Dibucaine hydrochloride (dibucaine hydrochloride) reduced the degradation of the BSA-gold complex in the depot body, which was not caused by inhibition of the parasite's overall proteolytic activity or reduced expression levels of cruzipain[1]. The quaternary ammonium compound, Dibucaine, reversibly inhibited SChE to minimal levels within 2 minutes. Inhibition is very effective. Its IC(50) is 5.3 microM for BuTch and 3.8 microM for AcTch. Compared with BuTch, the inhibition was competitive with K(i) of 1.3 microM; while compared with AcTch, the inhibition constant was linear mixed (competitive/non-competitive), with inhibition constants K(i) and K(I) are 0.66 and 2.5 microM, respectively. Dibucaine has a butoxyl side chain similar to the butyl group of BuTch and is longer than the ethylene group of AcTch [2].
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- Since: 2014-09-09
- Address: No.28 Hua Long Road,Ji Nan City,China