Product Details
| Product Name:
GT 949 |
CAS No.:
460330-27-2 |
| Purity:
99.95% |
Supply Ability:
10g |
| Release date:
2025/11/09 |
Product Introduction
Bioactivity
| Name | GT 949 |
| Description | GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) with an EC50 of 0.26 nM. |
| In vitro | GT 949 displays selectivity to EAAT2 and has no effect on glutamate activity mediated by EAAT1 or EAAT3. GT 949 improves glutamate transport (EC50 = 0.26 nM) and increases glutamate transport in a non-competitive manner with an increase in Vmax of about 47% in EAAT2-transfected cells[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.79 mM), Sonication is recommended.
DMSO : 55 mg/mL (104.23 mM), Sonication is recommended.
|
| Keywords | GT-949 | GT949 | GT 949 | EAAT2 |
| Inhibitors Related | MSNBA | Fraxin | LDN-212320 | Venuloside A | Brilliant Yellow | WAY-213613 hydrochloride | Jujuboside A | IPN60090 | SLC26A3-IN-1 | BAY-876 | Phloretin | Telaglenastat |
| Related Compound Libraries | Bioactive Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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