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Postion:Product Catalog >Organic Chemistry>Carboxylic acids and derivatives>Acyclic carboxylic acid>Heptafluorobutyric acid
Heptafluorobutyric acid
  • Heptafluorobutyric acid

Heptafluorobutyric acid

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 10000
Update Time: 2023-05-03

Product Details

Product Name: Heptafluorobutyric acid CAS No.: 375-22-4
Min. Order: 1KG Purity: 95% ,98%
Supply Ability: 10000 Release date: 2023/05/03
Product NameHeptafluorobutyric acid
 Model NoSIL136F
 Cas No.375-22-4
 Assay95% ,98%
 Molecular StructuralArticle illustration
 Details:
 
Product Name:Heptafluorobutyric acid 
Chemical Properties:Clear colorless to faintly yellow liquid 
CAS:375-22-4 
MF:C4HF7O2
MW:214.04
Melting point -17.5 °C
Boiling point :120 °C755 mm Hg(lit.)
Density:1.645 g/mL at 25 °C(lit.)
Vapor density :7 (vs air)
Vapor pressure:~10 mm Hg ( 25 °C)
Refractive index :n20/D 1.3(lit.)
Fp :120-121°C
Storage temp. :Store below +30°C.
Pka:pK1:0.17 (25°C)
Specific Gravity:approximate 1.6 
PH:1 (H2O, 20℃)
Water Solubility:miscible  

Uses:Heptafluorobutyric acid (HBFA) has been used widely for purifying neuropeptides because of its excellent resolution. The use of heptafluorobutyric acid as a volatile ion-pair reagent in the high-performance liquid chromatographic isolation of SB-223070 John K.
Heptafluorobutyric acid is a strong acid and ion-pairing agent that is used in analytical chemistry, notably in HPLC and in gas chromatography/mass spectrometry (GC/MS), in a similar manner to trifluoroacetic acid (TFA). The strong acidity of HFBA ensures that other acidic groups such as carboxylic acid moieties on biomolecules remain protonated, and thus the biomolecule samples are able to interact with organic solvents in such processes as reverse phase chromatography. The longer alkyl chain of HFBA makes it more hydrophobic than TFA, and thus HFBA can be utilized with more hydrophobic samples.

HFBA (0.1%) has been used in the mobile phase of an HPLC/LC-MS protocol for the detection of marine bacterioplankton sideophores.A study of the effects of various acids, including HFBA, on the resolution of intact proteins by reversed-phase LC/ESI-MS has been published.A modified version of the peptide ladder sequencing technique that incorporates allyl isothiocyanate and HFBA has been reported.

Heptafluorobutyric acid is an ion pair reagent for reverse-phase HPLC. It is used in the sequencing, synthesis, and solubilizing of proteins and peptides. It is used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It is an effective additive for zinc electrodeposition.

Perfluorobutyric acid was used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It was used as ion pairing reagent in preparative and analytical reserved phase HPLC of underivatised peptides.
Perfluorobutyric acid is an effective additive for zinc electrodeposition.


Company Profile Introduction

Silworld is a young, dynamic and Full-service supplier and distributor of speciality chemical products in plating intermediate for Ni,Cu,Zn ,medicine intermediate,fluoro chemical such as Perfluorinated surfactants, Hydrogen fluoride ether, Fluorotelomer, Fluorine monomer, fine chemical and representing quality manufacturers around the world. These strong and narrow partnerships with the producers , give the advantage to the customers, to get a very competitive prices, a short delivery time, the important and indispensable documents for his work, and at all events, a common business in the mutual respect and the transparency . Silworld continues to grow, to diversify and to serve as a sourcing specialist by developing relationships with producers around the world to other fields and answering the wishes of customers and their specific requests.

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