Hydroxyecdysone
| Price | $10 |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | Ex 20 tons |
| Update Time: | 2022-10-10 |
Product Details
| Product Name: Hydroxyecdysone | CAS No.: 5289-74-7 |
| EC-No.: 811-097-1 | Min. Order: 1kg |
| Purity: 99% | Supply Ability: Ex 20 tons |
| Release date: 2022/10/10 |
Use of Hydroxyecdysone
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Cyanotis arachnoides C.B.Clarke which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1].Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2].
| Name | 20-hydroxyecdysone |
|---|---|
| Synonym | More Synonyms |
| Description | Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Cyanotis arachnoides C.B.Clarke which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1].Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2]. |
|---|---|
| Related Catalog | Research Areas >> Cardiovascular Disease Signaling Pathways >> Apoptosis >> Caspase Signaling Pathways >> Autophagy >> Autophagy |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere |
| SMILES | O[C@@H]1[C@H](O)C[C@](C(C=C2[C@]3([H])CC[C@@]4(C)[C@@]2(O)CC[C@]4([H])[C@](O)(C)[C@H](O)CCC(O)(C)C)=O)([H])[C@]3(C)C1 |
| References | [1]. Liu H, et al. E93 predominantly transduces 20-hydroxyecdysone signaling to induce autophagy and caspase activity in Drosophila fat body. Insect Biochem Mol Biol. 2014 Feb;45:30-9. [2]. Phungphong S, et al. 20-Hydroxyecdysone attenuates cardiac remodeling in spontaneously hypertensive rats. Steroids. 2017 Oct;126:79-84. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 702.1±60.0 °C at 760 mmHg |
| Melting Point | 242-244 °C |
| Molecular Formula | C27H44O7 |
| Molecular Weight | 480.634 |
| Flash Point | 392.4±29.4 °C |
| Exact Mass | 480.308716 |
| PSA | 138.45000 |
| LogP | -0.53 |
| Vapour Pressure | 0.0±5.0 mmHg at 25°C |
| Index of Refraction | 1.597 |
| Storage condition | 2-8°C |
| Water Solubility | alcohol: soluble |
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