Idebenone NEW

Idebenone CAS:58186-27-9 With High Purity

Product Name:Idebenone

Synonyms:cv 2619 idebenone;Daruma：Mnesis;2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-;6-(10-Hydroxydecyl)ubiquinone;2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione;Idebenon;2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone;IDEBENONE(P)

CAS:58186-27-9

MF:C19H30O5

MW:338.44

EINECS:  1308068-626-2

Melting point:52-550C

Boiling point:497.3±45.0 °C(Predicted)

density:1.08±0.1 g/cm3(Predicted)

storage temp.:room temp

solubility:Soluble in DMSO (up to 25 mg/ml).

Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Chemical Properties:An odorless yellow-orange crystalline solid. It is highly insoluble in water, but can be easily dissolved in chloroform, methanol, or absolute ethanol. It is also soluble in ethyl acetate, but insoluble in n-hexane.

Application   

Idebenone is ubiquinone derivative with protective effects against cerebral ischemia and cognition enhancer. It has been used:

chemotherapy drug

to treat mutant myocilin (mMYOC) cells for drug treatment assay

to validate C2C12 secondary cell screening assay

to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs