Isopropyl acetoacetate NEW

Isopropyl acetoacetate is an organic compound belonging to the ester family, derived from acetoacetic acid and isopropyl alcohol. Below is a detailed breakdown of its properties and uses:

Chemical Structure

• Formula: C₇H₁₂O₃

• Structure: (CH₃)₂CHOOCCH₂COCH₃

• Composed of an isopropyl group ((CH₃)₂CH-) esterified to the carboxylate group of acetoacetic acid (CH₃COCH₂COOH).

Physical Properties

• Likely a liquid at room temperature with a fruity odor, typical of many esters.

• Boiling point/Melting point: Specific values depend on purity but are consistent with similar mid-weight esters.

Synthesis

• Formed via esterification of acetoacetic acid with isopropyl alcohol, releasing water.

Applications

1. Organic Synthesis:

• Key in the acetoacetic ester synthesis, a method to prepare ketones through alkylation or acylation at the alpha-carbon, followed by hydrolysis and decarboxylation.

• The isopropyl group may alter solubility or reactivity compared to ethyl or methyl analogs (e.g., ethyl acetoacetate).

2. Industrial Uses:

• Potential solvent or intermediate in pharmaceuticals, agrochemicals, or polymer chemistry (e.g., as a plasticizer or monomer precursor).