lumateperone (Tosylate)
| Price | $16000 |
| Package | 1000g |
| Min. Order: | 1g |
| Supply Ability: | 50KG |
| Update Time: | 2023-11-01 |
Product Details
| Product Name: lumateperone (Tosylate) | CAS No.: 1187020-80-9 |
| Min. Order: 1g | Purity: 99.0%min singleimpurity 0.5%max |
| Supply Ability: 50KG | Release date: 2023/11/01 |
Lumateperone tosylate (ITI-007) is an orally active, potent 5-HT2A antagonist, postsynaptic D2 antagonist, and serotonin transporter SERT inhibitor (Ki = 0.5, 32, 62 nM, respectively) with in vivo antipsychotic efficacy and no effect toward receptors associated with cognitive and metabolic side effects of antipsychotic drugs (e.g., H1, 5-HT2C, muscarinic). ITI-007 blocks DOI-induced headtwitch (ID50 = 0.09 mg/kg, po.) and D-AMPH-induced hyperlocomotion in mice (ID50 = 0.95 mg/kg, po.), while also acting as a partial agonist at presynaptic striatal D2 receptors.
Company Profile Introduction
Our company specializes in the research, development and production of APIs and pharmaceutical intermediates. At the same time, our core R&D team has more than 20 years of drug R&D experience. Under the support of a good research and development environment and a professional technical team, our company has obtained rich experience and outstanding achievements of new drugs and generic drugs projects. On the one hand, we are focused on the research and development and the optimization of production processes of generic drugs such as anti-viral and anti-malaria. On the other hand, we are also committed to the cooperative development of innovative drugs in the fields of respiratory system and hypoglycemia. We can provide technical support in all key links of drug research and development for drug production and distribution companies.
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China- Since: 2006-07-19
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