Product Details
| Product Name: Mavacamten | CAS No.: 1642288-47-8 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 10000kg | Release date: 2025/04/02 |
Manufacturer Provide Mavacamten Myk-461 (SAR-439152) Powder CAS 1642288-47-8
Introduction
Product Name: Mavacamten
Other Name :Mavacamten (MYK-461
CAS NO:1642288-47-8
Purity: 99%min
Appearance:White crystalline powder
Molecular formula:C15H19N3O2
MW:273.33
Density:1.19±0.1 g/cm3(Predicted)
Storage :Keep in dark place,Inert atmosphere,Room temperature
MYK-461 reduces the activity of homeostasis ATPASE by inhibiting the phospharic acid release rate of β -myocardial myosin -S1. MYK-461 regulates several steps in the myosin chemo-mechanical cycle: in addition to reducing the rate-limiting step (phospharic acid release) in this cycle, MYK-461 also reduces the number of myosin-S1 heads that interact with actin filaments during the transition from weak to strong binding states. MYK-461 also reduced the binding rate of myosin to ADP-actin and the release rate of ADP from Myosin-S1.
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