Mirk-IN-1 NEW
| Price | $368 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-12 |
Product Details
| Product Name: Mirk-IN-1 | CAS No.: 1386979-55-0 |
| Supply Ability: 10g | Release date: 2024/11/12 |
Product Introduction
Bioactivity
| 名称 | Mirk-IN-1 |
| 描述 | Mirk-IN-1 is an effective inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A (IC50: 68±48 nM and 22±8 nM respectively). |
| 体外活性 | Dyrk inhibitor Mirk-IN-1 had an EC50 of 1.9 ±0.2 mmol/L on SW620 cells. Mirk-IN-1 inhibited the activities of DYRK1A, ABL, FLT3, and MARK1 by 88%, 64%, 56%, and 73%, respectively, at a much higher concentration of 10 mmol/L in a kinase assay [1]. Mirk-IN-1 was able to block tumour cells from undergoing reversible arrest in a quiescent G0 state and enable some cells to exit quiescence [2]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 5 mg/mL (10.03 mM), Sonication is recommended. |
| 关键字 | MirkIN1 | Mirk-IN-1 | Mirk IN 1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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