N-Succinimidyl 3-(Bromoacetamido)propionate NEW
| Price | Get Latest Price |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: N-Succinimidyl 3-(Bromoacetamido)propionate | CAS No.: 57159-62-3 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | N-Succinimidyl 3-(Bromoacetamido)propionate |
| Description | N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker used in the synthesis of PROTACs and antibody-drug conjugates (ADCs) [1, 2], serving as a cleavable ADC linker to facilitate drug-antibody conjugation for targeted delivery [2]. |
| In vitro | PROTACs contain two ligands joined by a linker: one binds to an E3 ubiquitin ligase, and the other to the target protein, utilizing the ubiquitin-proteasome system to selectively degrade target proteins [1]. ADCs consist of an antibody linked to an ADC cytotoxin through an ADC linker [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | PEGs | N-Succinimidyl 3-(Bromoacetamido)propionate | NSuccinimidyl 3(Bromoacetamido)propionate | N Succinimidyl 3 (Bromoacetamido)propionate | Cleavable | Alkyl/ether | ADCLinker | ADC Linker |
| Inhibitors Related | N-Boc-PEG5-bromide | Boc-C16-COOH | Boc-Val-Cit-OH | Succinic anhydride | DSS Crosslinker | Fmoc-8-amino-3,6-dioxaoctanoic acid | Fmoc-Gly-Gly-OH | SMCC | Boc-NH-PEG4-CH2COOH | EMCS | DSP Crosslinker | DSG Crosslinker |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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