PGS-IN-1 NEW

Price	$44	$98	$179
Package	1mg	5mg	10mg

Min. Order:
Supply Ability:	10g
Update Time:	2025-04-28

Product Details

Product Name: PGS-IN-1	CAS No.: 102271-49-8
Purity: 99.67%	Supply Ability: 10g
Release date: 2025/04/28

Product Introduction

Bioactivity

Name	PGS-IN-1
Description	PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).
In vitro	PGS-IN-1 is the trans isomer of the synthesized α-benzulidene-γ-butyrolactone. PGS-IN-1 exhibits potent anti-inflammatory and PGS inhibitory activity with IC50 of 0.28 μM[1]. PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase with IC50 of 1.05 μM[1].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 55 mg/mL (181.87 mM), Sonication is recommended.
Keywords	ProstaglandinReceptor \| prostaglandin synthetase (PGS) \| Prostaglandin Receptor \| Prostaglandin E synthase \| PGS-IN-1 \| PGSIN1 \| PGS IN 1 \| PGE synthase \| LOX \| Lipoxygenase \| KME4 \| KME 4 \| Inhibitor \| inhibit \| 5-Lipoxygenase
Inhibitors Related	Pranoprofen \| 2,5-Di-tert-butylhydroquinone \| Tranilast \| Caffeic Acid \| 5-LOX inhibitor \| Resveratrol \| Rutin \| NNK \| Ozagrel \| Ethamsylate \| 5-Aminosalicylic Acid \| Malotilate
Related Compound Libraries	Pain-Related Compound Library \| Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| ReFRAME Related Library \| Anti-Obesity Compound Library \| Inhibitor Library \| Metabolism Compound Library \| Lipid Metabolism Compound Library \| Immunology/Inflammation Compound Library \| Bioactive Compounds Library Max \| GPCR Compound Library \| Anti-Cancer Compound Library

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR

United States

Since: 2011-01-07
Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA

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