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Postion:Product Catalog >PI-828
PI-828
  • PI-828

PI-828 NEW

Price $30 $71 $119
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-11-10

Product Details

Product Name: PI-828 CAS No.: 942289-87-4
Purity: 99.95% Supply Ability: 10g
Release date: 2025/11/10

Product Introduction

Bioactivity

NamePI-828
DescriptionPI-828 is a phosphatidylinositol 3-kinase (PI3K) inhibitor, which is widely used to study the physiological function of PI3K and also promotes stem cell differentiation into mesoderm.
In vitroPI-828 (0.78-3.12 µM; 48 hours) reduces caspase 3 activation. However, higher concentrations of PI-828 (6.25-12.5 μM) alone causes apoptosis[2].The sensitivity to PI-828 is a key feature of PI3K-C2β that shows a different sensitivity to this inhibitor compared to class I PI3Ks. Of note, 1 μM PI-828 has no effect on the activity of PI3K-C2β, while it significantly inhibits class I PI3Ks. In particular, a concentration of 10 μM PI-828 completely blocks class I PI3Ks, whereas it has only a partial inhibitory effect on PI3K-C2β[4]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (3.1 mM), Sonication is recommended.
DMSO : 11.2 mg/mL (34.74 mM), Sonication is recommended.
KeywordsPI-828 | PI828 | PI 828 | p110α | LY-294002, 4gamma-NH2 | CK2α2 | CK2 | CaseinKinase | Casein Kinase
Inhibitors RelatedMyricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | Emodin | 3-Methyladenine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | Inavolisib | Quercetin Dihydrate | Apilimod
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Anti-Cancer Metabolism Compound Library | Hematonosis Compound Library | Anti-Breast Cancer Compound Library | Anti-Obesity Compound Library | Antioxidant Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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