pramiracetam NEW

pramiracetam

Modify Date: 2025-08-20 08:21:58

pramiracetam structure	Common Name	pramiracetam
	CAS Number	68497-62-1	Molecular Weight	269.383
	Density	1.0±0.1 g/cm3	Boiling Point	461.0±30.0 °C at 760 mmHg
	Molecular Formula	C14H27N3O2	Melting Point	47 °C
	MSDS	ChineseUSA	Flash Point	232.6±24.6 °C
	Symbol	GHS07	Signal Word	Warning

Purity		Quantity		Budget		Inquiry

Use of pramiracetam Pramiracetam is a nootropic drug derived from piracetam, and is more potent. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries. IC50 Value: Target: in vitro: Pramiracetam sulfate did not exhibit any affinity in vitro for dopaminergic , GABAergic, serotoninergic, adrenergic, muscarinic, adenosine (IC50 > 10 uM), and benzodiazepine receptors (IC50 > 1 uM) binding sites [1].in vivo: In a double-blind, randomized design, two groups of six subjects each received alternating placebo and single 400, 800, 1,200, and 1,600 mg oral doses of pramiracetam after an overnight fast. Mean (+/- SD) peak plasma concentrations of the four dose groups (2.71 +/- 0.54, 5.40 +/- 1.34, 6.13 +/- 0.71, 8.98 +/- 0.71 micrograms/mL) were attained between two to three hours following drug administration [2]. Two doses of pramiracetam (7.5 mg/kg and 15 mg/kg) were administered daily prior to testing for 7 weeks in a 16-arm radial maze in which nine arms were baited with food [3].

• Properties

• Articles23

• Spectrum

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 Names

Name	Pramiracetam Hydrate
Synonym	More Synonyms

 pramiracetam Biological Activity

Description	Pramiracetam is a nootropic drug derived from piracetam, and is more potent. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries. IC50 Value: Target: in vitro: Pramiracetam sulfate did not exhibit any affinity in vitro for dopaminergic , GABAergic, serotoninergic, adrenergic, muscarinic, adenosine (IC50 > 10 uM), and benzodiazepine receptors (IC50 > 1 uM) binding sites [1].in vivo: In a double-blind, randomized design, two groups of six subjects each received alternating placebo and single 400, 800, 1,200, and 1,600 mg oral doses of pramiracetam after an overnight fast. Mean (+/- SD) peak plasma concentrations of the four dose groups (2.71 +/- 0.54, 5.40 +/- 1.34, 6.13 +/- 0.71, 8.98 +/- 0.71 micrograms/mL) were attained between two to three hours following drug administration [2]. Two doses of pramiracetam (7.5 mg/kg and 15 mg/kg) were administered daily prior to testing for 7 weeks in a 16-arm radial maze in which nine arms were baited with food [3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Warner Lambert, et al. Some Neurochemical Properties of Pramiracetam (CI-879), A New Cognition-Enhancing Agent. [2]. Chang T, et al. Pharmacokinetics of oral pramiracetam in normal volunteers. J Clin Pharmacol. 1985 May-Jun;25(4):291-5.

 Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	461.0±30.0 °C at 760 mmHg
Melting Point	47 °C
Molecular Formula	C14H27N3O2
Molecular Weight	269.383
Flash Point	232.6±24.6 °C
Exact Mass	269.210327
PSA	52.65000
LogP	0.39
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.495
Storage condition	2-8°C

 MSDS

pramiracetam MSDS(Chinese)

 Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
Risk Phrases	22
RIDADR	NONH for all modes of transport
HS Code	2942000000

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