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Postion:Product Catalog >Chemical Reagents>Organic reagents>Carboxylic anhydride>Propionic anhydride
Propionic anhydride
  • Propionic anhydride
  • Propionic anhydride
  • Propionic anhydride
  • Propionic anhydride
  • Propionic anhydride

Propionic anhydride NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-09-14

Product Details

Product Name: Propionic anhydride CAS No.: 123-62-6
EC-No.: 204-638-2 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/09/14

CAS:123-62-6
MF:C6H10O3
MW:130.14
EINECS:204-638-2
Product Categories:Biochemicals and Reagents;Carboxylic Acid Anhydrides;Fatty Acids and conjugates;Fatty Acyls;Saturated Fatty Acids and Derivatives;Anhydrides;Organics;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Lipids;Organic Building Blocks;Acylation Reagent;bc0001
Mol File:123-62-6.mol
Article illustration

Propionic anhydride Chemical Properties
Melting point -42 °C
Boiling point 167 °C(lit.)
density 1.015 g/mL at 25 °C(lit.)
vapor density 4.5 (vs air)
vapor pressure 10 mm Hg ( 57.7 °C)
refractive index n20/D 1.404(lit.)
Fp 165 °F
storage temp. Store below +30°C.
solubility H2O: decomposes (when in contact with water)
form clear liquid
color Colorless to Almost colorless
Odorlike acetaldehyde
PH2.5 (100g/l, H2O, 20℃)(calculated on the free acid)
explosive limit1.3-9.5%(V)
Water Solubility hydrolyses
Sensitive Moisture Sensitive
Merck 14,7826
BRN 507066
Stability:Stable. Combustible. Incompatible with strong oxidizing agents, water, moisture, most common metals, active halogen compounds, ammonia, amines.
LogP0.33 at 20℃
CAS DataBase Reference123-62-6(CAS DataBase Reference)
NIST Chemistry ReferencePropanoic acid, anhydride(123-62-6)
EPA Substance Registry SystemPropionic anhydride (123-62-6)


Propionic anhydride Usage And Synthesis
Chemical PropertiesPropionic anhydride is a colorless liquid. Strong, pungent, unpleasant odor. Soluble in methanol, ethanol, ether, chloroform and alkali, decomposes in water.
UsesPropionic anhydride is used as a esterifying agent for certain perfume oils, fats, oils, and especially cellulose and as a reagent in organic synthesis. In the production of alkyd resins, dyestuffs and drugs. Has been used as a dehydrating agent in some sulfonations and nitrations.
ApplicationPropionic anhydride was previously used in the preparation of α and β-1-propionyl derivatives of glucopyranose tetra-acetate.
General DescriptionPropionic anhydride is an organic compound with the molecular formula (CH3CH2CO)2O. it is an colorless acid anhydride that is widely used as a reagent in organic synthesis.
Air & Water ReactionsDecomposes exothermically in water to form a corrosive solution of propionic acid [Merck, 11th ed. 1989].
Reactivity ProfilePropionic anhydride reacts exothermically with water. The reactions are sometimes slow, but can become violent when local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
HazardStrong irritant to tissue.
Health HazardInhalation causes irritation of eyes and respiratory tract. Contact with liquid causes burns of eyes and skin. Ingestion causes burns of mouth and stomach.
Fire HazardCombustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Flammability and ExplosibilityNon flammable
Safety ProfileModerately toxic by ingestion. Mildly toxic by skin contact. A corrosive irritant to skin, eyes, and mucous membranes. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. Used as an esterifyng agent and dehydrating agent. See also ANHYDRIDES.
SafetyPropanoic anhydride is strong smelling and corrosive, and will cause burns on contact with skin. Vapour can burn eyes and lungs.
SynthesisPropanoic anhydride has been prepared by dehydration of propanoic acid using ketene :
2 CH3CH2CO2H + CH2= C= O → (CH3CH2CO)2O + CH3CO2H.
Potential ExposureUsed in the manufacture of perfumes, flavorings, alkyd resins; dyestuffs, pharmaceuticals; as an esterifying agent for fats, oils, and cellulose; dehydrating medium for nitrations and sulfonations.
ShippingUN2496 Propionic anhydride, Hazard class: 8; Labels: 8-Corrosive material.
Purification MethodsShake the anhydride with P2O5 for several minutes, then distil. [Beilstein 2 IV 722.]
IncompatibilitiesVapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, perox- ides, permanganates, perchlorates, chlorine, bromine, fluo- rine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, reducing agents; alcohols and metals. Contact with water forms heat 1 flammable propionic acid. Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercap- tans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur).
Waste DisposalUse a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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