(Rac)-5-Hydroxymethyl Tolterodine hydrochloride NEW
| Price | $163 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: (Rac)-5-Hydroxymethyl Tolterodine hydrochloride | CAS No.: 250214-40-5 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | (Rac)-5-Hydroxymethyl Tolterodine hydrochloride |
| Description | (Rac)-5-Hydroxymethyl Tolterodine hydrochloride, also known as (Rac)-Desfesoterodine hydrochloride, is an active metabolite of Tolterodine that functions as a mAChR antagonist. It exhibits significant affinity (K i values) for M1, M2, M3, M4, and M5 receptors, with values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM, respectively. This compound is commonly employed in research related to overactive bladder conditions. |
| In vitro | In vitro, (Rac)-5-Hydroxymethyl Tolterodine (PNU-200577) hydrochloride demonstrates competitive, concentration-dependent inhibition of carbachol-induced contraction in isolated guinea-pig urinary bladder strips, with a binding affinity (K B) of 0.84 nM and a potency of 9.14 (pA2)[2]. |
| In vivo | Treatment with (Rac)-5-Hydroxymethyl Tolterodine (5-HMT; 0.88 μmol/kg; i.v.) hydrochloride demonstrates significant binding activity to muscarinic receptors across all tissues, barring the cerebral cortex, and exhibits prolonged activity in the bladder[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Desfesoterodine Hydrochloride | (Rac)5Hydroxymethyl Tolterodine hydrochloride | 5-Hydroxymethyl Tolterodine Hydrochloride | (Rac) 5 Hydroxymethyl Tolterodine hydrochloride | PNU-200577hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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