Rosiglitazone hydrochloride NEW
| Price | $33 | $45 | $62 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-04 |
Product Details
| Product Name: Rosiglitazone hydrochloride | CAS No.: 302543-62-0 |
| Purity: 99.79% | Supply Ability: 10g |
| Release date: 2025/12/04 |
Product Introduction
Bioactivity
| Name | Rosiglitazone hydrochloride |
| Description | Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. |
| In vitro | Bafetinib blocks WT Bcr-Abl autophosphorylation and its downstream kinase activity with IC50 of 11 nM and 22 nM in K562 and 293T cells, respectively. Bafetinib suppresses the growth of the Bcr-Abl-positive cell lines including K562, KU812, and BaF3/wt cells potently without effects on the proliferation of the Bcr-Abl-negative U937 cell line. Moreover, Bafetinib exhibits a dose-dependent antiproliferative effect against Bcr-Abl point mutant cell lines, such as BaF3/E255K cells. [1] In Bcr-Abl+ leukemia cell lines, Bafetinib induces both caspase-mediated and caspase-independent cell death by blocking the phosphorylation of Bcr-Abl. [2] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (25.39 mM), Sonication is recommended. Ethanol : 73 mg/mL (185.33 mM), Sonication is recommended. DMSO : 73 mg/mL (185.33 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | TRPVChannel | TRPV Channel | TRPChannel | TRP Channel | Transient receptor potential channels | smoke | senescence | Rosiglitazone Hydrochloride | Rosiglitazone hydrochloride | Rosiglitazone | PPARγ | PPAR | Peroxisome proliferator-activated receptors | ovarian cancer | neuroprotection | mellitus | Inhibitor | inhibit | hepatocellular | HCC | Ferroptosis | diabetic | diabetes | carcinoma | cancer | BRL-49653 | BRL49653 | BRL 49653 | bladder | Autophagy | Apoptosis | antihyperglycemic |
| Inhibitors Related | Stavudine | Aceglutamide | Cysteamine hydrochloride | Hydroxychloroquine | Daidzein | Metronidazole | Guanidine hydrochloride | Paeonol | Naringin | Dimethyl phthalate | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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