TDI-011536 NEW
| Price | $51 | $80 | $172 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-10 |
Product Details
| Product Name: TDI-011536 | CAS No.: 2687970-96-1 |
| Purity: 99.53% | Supply Ability: 10g |
| Release date: 2025/11/10 |
Product Introduction
Bioactivity
| Name | TDI-011536 |
| Description | TDI-011536, a potent Lats kinase inhibitor, disrupts Hippo-Yap signaling and promotes the proliferation of lesioned heart muscle cells. This compound is valuable for research in organ conservation and regeneration. |
| In vitro | TDI-011536 (3 µM; 24 h) reduces Yap phosphorylation and (3 µM; 5 days) induces Müller glia proliferation in human retinal organoids[1]. |
| In vivo | TDI-011536 (200 mg/kg; i.p.; once) inhibits Lats and reduces pYap levels for over 4 hours in the liver, heart, and skin, while TDI-011536 (100 mg/kg; i.p.; once daily for 2 or 3 days) exhibits a proliferative effect on cardiomyocytes[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (137.2 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.49 mM), Sonication is recommended. |
| Keywords | TDI-011536 | TDI011536 | TDI 011536 |
| Inhibitors Related | AICAR | MY-1076 | YAP-TEAD-IN-3 | Verteporfin | DC-TEADin02 | Pipecolic acid | MSC-4106 | VT103 | VT107 | PY-60 | VT104 | MYF-01-37 |
| Related Compound Libraries | Bioactive Compound Library | Kinase Inhibitor Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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