VPC-14449 NEW
| Price | $269 | $432 | $689 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-10 |
Product Details
| Product Name: VPC-14449 | CAS No.: 1621375-32-3 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2025/11/10 |
Product Introduction
Bioactivity
| Name | VPC-14449 |
| Description | VPC-14449 is a selective androgen receptor DNA-binding domain (AR-DBD) inhibitor, useful in prostate cancer research. |
| In vitro | Methods: LNCaP, C4-2, MR49F, and 22Rv1 cells were treated with VPC-14449 (0.01-100 μM, 24 hours) to test its inhibitory effect on AR-V7 transcriptional activity in cells. Results: VPC-14449 inhibited AR transcriptional activity and cell viability in LNCaP, C4-2, MR49F, and 22Rv1 cells.[1] |
| In vivo | Methods: Castrated mice were given VPC-14449 (100 mg/kg, ip, for 4 weeks) twice daily and LNCaP xenograft tumor volume and serum PSA were assessed. Results: VPC-14449 reduced tumor volume and abolished PSA production in the LNCaP xenograft model.[1] |
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100 mg/mL (253.75 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (10.15 mM), Sonication is recommended. |
| Keywords | VPC-14449 | VPC 14449 |
| Inhibitors Related | Dehydroisoandrosterone 3-acetate | Bicalutamide | Chlormadinone acetate | S-23 | Bavdegalutamide | Enzalutamide | Octinoxate | Nandrolone phenylpropionate | Allura Red AC | Sunset Yellow FCF | Ostarine | Flutamide |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $82.00/1mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-09-22 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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