Product Details
| Product Name:
Z164597606 |
CAS No.:
1050587-57-9 |
| Supply Ability:
10g |
Release date:
2025/10/27 |
Product Introduction
Bioactivity
| Name | Z164597606 |
| Description | Z164597606 is a compound that acts as a selective inhibitor of the enzyme Butyrylcholinesterase (BChE), with IC50 values of 1.3 μM and 1.7 μM for equine BChE and human BChE, respectively. Through a π-π stacking interaction, Z164597606 specifically interacts with the amino acid Trp82 of human BChE. This compound has potential applications in Alzheimer's disease research [1] [2]. |
| In vitro | Z164597606 at a concentration of 10 μM potently reduces BChE activity while demonstrating minimal inhibition (not exceeding 30%) of AChE, according to study [1]. At concentrations ranging from 0.5 to 20 μM, Z164597606 likely targets the catalytic anionic site (CAS) of BChE, as inferred from Lineweaver-Burk reciprocal plots [1]. Furthermore, Z164597606 has been shown to be non-toxic to the neuronal cell line SH-SY5Y at concentrations of 10 and 50 μM [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Fenobucarb | 1-Naphthyl acetate | Ethyl (triphenylphosphoranylidene) acetate | Methylene Violet 3RAX | 4-Methylbenzylidene camphor | Isoeugenol acetate | Diethyltoluamide | 1-Methoxy-3-methylbenzene | Coumaran | Dimethyl sulfoxide | Methyl tridecanoate | Trimethylammonium chloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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