ChemicalBook >>N-Benzyloxycarbonyl-L-proline>>Z-Pro-OH(1148-11-4)

Z-Pro-OH(1148-11-4)

Z-Pro-OH(1148-11-4)
Product IdentificationBack to Contents
【Product Name】

Z-Pro-OH
【Synonyms】

(S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-
1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, L-
N-[(Phenylmethoxy)carbonyl]-L-proline
N-Benzyloxycarbonyl-(S)-proline
N-Cbz-L-proline
【CAS】

1148-11-4
【Formula】

C13H15NO4
【Molecular Weight】

249.26
【EINECS】

214-557-4
【RTECS】

UY0745000
【RTECS Class】

Reproductive Effector
【Beilstein/Gmelin】

88579
【Beilstein Reference】

5-22-01-00084
Physical and Chemical PropertiesBack to Contents
【Appearance】

White powder.
【Solubility in water】

Very soluble
【Melting Point】

91 - 93.5
【Boiling Point】

383
【pKa/pKb】

3.82 (pKa)
【Partition Coefficient】

1.57
【Usage】

An inhibitor of prolidase.
First Aid MeasuresBack to Contents
【Ingestion】

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Ingestion】

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
【EC Safety Phrase】

S 22 24/25
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

Reproductive effects have been reported in animals.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing agents.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
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