ChemicalBook >>Mometasone furoate>>9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate(83919-23-7)

9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate(83919-23-7)

9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate(83919-23-7)
Product IdentificationBack to Contents
【Product Name】

9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate
【Synonyms】

Mometasone 17-(2-furoate)
Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methyl-, (11-beta,16-alpha)
【CAS】

83919-23-7
【Formula】

C27H30Cl2O6
【Molecular Weight】

521.44000000000005
【RTECS】

TU3822000
【Merck】

12,6324
【Beilstein/Gmelin】

4340538
Physical and Chemical PropertiesBack to Contents
【Appearance】

Distributed as 0.1% ointment with a petrolatum base.
【Solubility in water】

Insoluble
【Melting Point】

218 - 220
【Vapor Pressure】

4.5E-18 (25 C)
【Density】

1.37 g/cm3 (20 C)
【pKa/pKb】

13.05 (pKa)
【Partition Coefficient】

4.27
【Usage】

Anti-inflammatory.
First Aid MeasuresBack to Contents
【Ingestion】

Give two glasses of water and induce vomiting. Never give anything by mouth to an unconscious person.
【Inhalation】

Supply fresh air. If required, provide artificial respiration. Keep patient warm. Seek immediate medical advice.
【Skin】

Wash thoroughly with soap and water.
【Eyes】

Flush with plenty of water for at least 15 minutes.
Handling and StorageBack to Contents
【Storage】

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Protective work clothing. Chemical protective gloves. Safety glasses or goggles.
【Exposure Effects】

May cause irritation of the eyes and skin. May cause reversible suppression of the Hypothalamic-Pituitary-Adrenal Axis, symptoms of Cushing’s Syndrome, hyperglycemia and glycosuria if ingested.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Extinguish with carbon dioxide, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Wear self-contained respirator. Wear fully protective impervious suit.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Assure slippery conditions are nullified. Add sand or dirt. Scoop up and remove, Wash area with soap and water.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing agents, bases.
【Stability】

Stable if stored as directed.
【Combustion Products】

May emit toxic fumes.
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