ChemicalBook >>Dexpanthenol>>(+)-Panthenol(81-13-0)

(+)-Panthenol(81-13-0)

(+)-Panthenol(81-13-0)
Product IdentificationBack to Contents
【Product Name】

(+)-Panthenol
【Synonyms】

(2R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
(R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
Dexpanthenol
【CAS】

81-13-0
【Formula】

C9H19NO4
【Molecular Weight】

205.25
【EINECS】

201-327-3
【RTECS】

ES4316000
【RTECS Class】

Drug; Primary Irritant
【Merck】

13,2964
【Beilstein/Gmelin】

1724947
【Beilstein Reference】

4-04-00-01652
Physical and Chemical PropertiesBack to Contents
【Appearance】

Odorless, colorless, viscous liquid.
【Solubility in water】

Very soluble
【Melting Point】

35 - 46
【Boiling Point】

484
【Vapor Pressure】

2E-11 (25 C)
【Density】

1.1 g/cm3 (20 C)
【pKa/pKb】

13.03 (pKa)
【Partition Coefficient】

-1.53
【Heat Of Vaporization】

86.3 kJ/mol
【Usage】

Provitamin b5 for cosmetic and pharmaceutical preparations.
【Vapor Density】

2.6
【Refractive Index】

1.4935 (20 C)
First Aid MeasuresBack to Contents
【Ingestion】

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Hazards IdentificationBack to Contents
【Inhalation】

Causes respiratory tract irritation. Can produce delayed pulmonary edema.
【Skin】

Causes skin irritation.
【Eyes】

Causes eye irritation. May cause chemical conjunctivitis.
【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

Effects may be delayed.
Fire Fighting MeasuresBack to Contents
【Flash Point】

246
【Autoignition】

385
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Upper exp. limit】

14.4
【Lower exp. limit】

2.4
【Fire Potential】

Combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Stability and ReactivityBack to Contents
【Incompatibilities】

Moisture, strong oxidizing agents.
【Stability】

Stable at room temperature in closed containers under normal storage and handling conditions.
【Decomposition】

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
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